Cardiac Effects in Long-Term Survivors of Hodgkin's and Non-Hodgkin's Lymphoma

This study has been terminated.
(not enough eligible patients)
Sponsor:
Information provided by (Responsible Party):
Louis Constine, University of Rochester
ClinicalTrials.gov Identifier:
NCT00903890
First received: May 15, 2009
Last updated: January 10, 2014
Last verified: January 2014
  Purpose

This study is to inquire by mailed survey regarding the cardiac and general health of patients previously treated for Hodgkin's and non-Hodgkin's lymphoma with radiation therapy/anthracycline chemotherapy.


Condition Intervention
Hodgkin Disease
Lymphoma, Non-Hodgkin
Other: Survey

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Cardiac Effects in Long-Term Survivors of Hodgkin's and Non-Hodgkin's Lymphoma After Radiation Therapy/Anthracycline Chemotherapy

Resource links provided by NLM:


Further study details as provided by University of Rochester:

Primary Outcome Measures:
  • Measure changes in Cardiac ejection fraction score [ Time Frame: Post Radiation Treatment ] [ Designated as safety issue: No ]
  • Measure changes in perfusion imaging score on the radionuclide cardiac profusion scan [ Time Frame: Post Radiation ] [ Designated as safety issue: No ]

Enrollment: 32
Study Start Date: August 2008
Estimated Study Completion Date: November 2014
Estimated Primary Completion Date: November 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
A
Individuals who have previously received radiation therapy and anthracycline chemotherapy for their Hodgkin's or non-Hodgkin's lymphoma.
Other: Survey
Survey asking questions regarding the subjects cardiac and general health.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients previously treated at the University of Rochester Department of Radiation Oncology.

Criteria

Inclusion Criteria:

  • All patients with Hodgkin's Lymphoma and Non Hodgkin's lymphoma who underwent Radiation Therapy (RT) to either a mantle or modified mantle field with or without adriamycin at the Wilmot Cancer Center at the University of Rochester are eligible for the study.

Exclusion Criteria:

  • Any severe preexisting cardiac disease (e.g., arrhythmia, angina, coronary disease, myocardial infarction, or congestive heart failure) prior to diagnosis
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00903890

Locations
United States, New York
University of Rochester Medical Center
Rochester, New York, United States, 14642
Sponsors and Collaborators
University of Rochester
  More Information

No publications provided

Responsible Party: Louis Constine, Professor, University of Rochester
ClinicalTrials.gov Identifier: NCT00903890     History of Changes
Other Study ID Numbers: ULYM07056
Study First Received: May 15, 2009
Last Updated: January 10, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Hodgkin Disease
Lymphoma
Lymphoma, Non-Hodgkin
Neoplasms by Histologic Type
Neoplasms
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases

ClinicalTrials.gov processed this record on August 21, 2014