Tissue Sample Collection From Patients With Fanconi Anemia - Full Text View

Sponsor:	Oregon Health and Science University
Information provided by:	National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:	NCT00899522

Purpose

RATIONALE: Collecting and storing samples of tumor tissue from patients with Fanconi anemia to test in the laboratory may help the study of cancer in the future.

PURPOSE: This laboratory study is collecting and storing tumor tissue samples from patients with Fanconi anemia.

Condition	Intervention
Fanconi Anemia Unspecified Adult Solid Tumor, Protocol Specific Unspecified Childhood Solid Tumor, Protocol Specific	Other: biologic sample preservation procedure Procedure: biopsy

Study Type:	Observational
Official Title:	Fanconi Anemia Cancer Cell Repository

Resource links provided by NLM:

MedlinePlus related topics: Anemia Cancer

U.S. FDA Resources

Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:

Creation of a Fanconi Anemia Cell Repository using rare solid tumor samples from patients with Fanconi anemia [ Designated as safety issue: No ]
Study tissue samples by molecular methods, including gene microarrays [ Designated as safety issue: No ]
Development of cancer cell lines from tissue archived from patients with Fanconi anemia [ Designated as safety issue: No ]

Study Start Date:

August 2005

Detailed Description:

OBJECTIVES:

Acquire rare solid tumor samples from patients with Fanconi anemia in order to create a Fanconi Anemia Cell Repository at the Oregon Health and Science University Cancer Institute.
Study repository tissue using a variety of molecular methods, including gene microarrays.
Develop cancer cell lines that are publicly available from tissue archived from patients with Fanconi anemia.

OUTLINE: Tumor biopsies are collected from patients with Fanconi anemia and archived for future molecular studies, cell line generation, and general usage by the research community at large. Medical information about the patient's cancer is also archived.

PROJECTED ACCRUAL: Not specified.

Eligibility

Ages Eligible for Study:	1 Year to 55 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

DISEASE CHARACTERISTICS:

Confirmed Fanconi anemia
Confirmed malignant solid tumor
Biopsy of tumor tissue available

PATIENT CHARACTERISTICS:

Not specified

PRIOR CONCURRENT THERAPY:

Not specified

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00899522

Locations

United States, Oregon
Knight Cancer Institute at Oregon Health and Science University	Recruiting
Portland, Oregon, United States, 97239-3098
Contact: Clinical Trials Office - Knight Cancer Institute at Oregon Hea 503-494-1080 trials@ohsu.edu

Sponsors and Collaborators

Oregon Health and Science University

Investigators

Principal Investigator:

Grover C. Bagby, MD

OHSU Knight Cancer Institute

More Information

Additional Information:

Clinical trial summary from the National Cancer Institute's PDQ® database This link exits the ClinicalTrials.gov site

No publications provided

Study ID Numbers:	CDR0000445453, OHSU-HEM-03022-LX, OHSU-IRB00001100, OSHU-CR00003822
Study First Received:	May 9, 2009
Last Updated:	May 9, 2009
ClinicalTrials.gov Identifier:	NCT00899522 History of Changes
Health Authority:	Unspecified

Keywords provided by National Cancer Institute (NCI):

Fanconi anemia
unspecified adult solid tumor, protocol specific
unspecified childhood solid tumor, protocol specific

Additional relevant MeSH terms:

Metabolic Diseases
Anemia, Hypoplastic, Congenital
Genetic Diseases, Inborn
Hematologic Diseases
Fanconi Anemia

DNA Repair-Deficiency Disorders
Anemia, Aplastic
Anemia
Bone Marrow Diseases

ClinicalTrials.gov processed this record on February 08, 2010