Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
RATIONALE: Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
PURPOSE: The purpose of this study is to collect and store samples of blood and tumor tissue from patients with osteosarcoma.
|Study Design:||Time Perspective: Retrospective|
|Official Title:||A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens|
- Collect biological specimens from patients with osteosarcoma [ Time Frame: baseline ] [ Designated as safety issue: No ]
- Provide a repository for long-term storage of osteosarcoma-related biological materials [ Time Frame: length of study ] [ Designated as safety issue: No ]
- Make these specimens available to qualified researchers to understand the biology of osteosarcoma [ Time Frame: length of study ] [ Designated as safety issue: No ]
- Correlate these results with the patients' clinical data [ Time Frame: lengh of study ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
serum, plasma and blood
|Study Start Date:||February 2008|
|Estimated Primary Completion Date:||January 2100 (Final data collection date for primary outcome measure)|
|Ancillary/Correlative All patients||Other: biologic sample preservation procedure|
- To collect biological specimens from patients with osteosarcoma at Children's Oncology Group (COG) institutions.
- To provide a repository for long-term storage of osteosarcoma-related biological materials.
- To make these specimens available to qualified researchers to understand the biology of osteosarcoma and correlate these results with the patients' clinical data.
OUTLINE: After the initial submission of blood samples, patients may undergo open or closed biopsy in order to obtain fresh and frozen tissue samples as well as paraffin embedded material. Patients who are enrolled at the time of initial diagnosis but then have a definitive surgery or develop recurrent disease may submit additional samples (paraffin block, frozen and fresh tumor tissue, or slides together with blood samples). Autopsy tumor samples may also be submitted.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00899275
Show 155 Study Locations
|Study Chair:||Richard Gorlick, MD||Children's Hospital at Montefiore|