SWOG-9245 Collecting and Storing Tissue Samples From Patients With Relapsed or Recurrent Non-Hodgkin Lymphoma After Treatment on a Southwest Oncology Group Clinical Trial
RATIONALE: Collecting and storing samples of tissue from patients with non-Hodgkin lymphoma to study in the laboratory may help the study of cancer in the future.
PURPOSE: This laboratory study is collecting and storing tissue samples from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial.
|Study Design:||Time Perspective: Retrospective|
|Official Title:||Central Lymphoma Repository Tissue Procurement Protocol for Relapse or Recurrent Disease|
- Acquisition of snap-frozen lymphoma tissues [ Time Frame: July 2011 ] [ Designated as safety issue: No ]
|Study Start Date:||March 1993|
|Study Completion Date:||July 2011|
|Primary Completion Date:||July 2011 (Final data collection date for primary outcome measure)|
- Acquire fresh snap-frozen lymphoma tissue from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial.
- Establish a standard set of procedures for routine acquisition, banking, and study of lymphoma tissues within the SWOG.
- Use repository tissue to establish clinical correlations via presently activated phenotyping studies and future projected molecular studies assessing specimen DNA and RNA status.
- Examine the biology of therapy failure in relationship to changes in pretreatment and post-treatment immunophenotypic data.
OUTLINE: This is a multicenter study.
Tissues collected at biopsy are snap-frozen and archived for future molecular and genetic studies.
PROJECTED ACCRUAL: Not specified
Show 82 Study Locations
|Study Chair:||Thomas Grogan, MD||University of Arizona|
|Study Chair:||Thomas P. Miller, MD||University of Arizona|
|Study Chair:||Richard I. Fisher, MD||James P. Wilmot Cancer Center|