Effect of Myoma Removal on Blood Pressure and Erythropoetin Level
The effect of myoma removal was studied on 28 patients with hypertension and myoma by holter monitoring and erythropoetin level check.
|Study Design:||Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Diagnostic
|Official Title:||Effect of Myoma Removal on Blood Pressure and Erythropoetin Level|
- 24 hour holter monitoring of blood pressure [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
- erythropoetin level [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
|Study Start Date:||May 2008|
|Study Completion Date:||March 2009|
|Primary Completion Date:||March 2009 (Final data collection date for primary outcome measure)|
Experimental: myoma, with or without hypertension
those with myoma with or without hypertension in holter monitoring
Procedure: myoma removal
surgical removal of myoma by hysterectomy
Myoma is the most common gynecoid tumor and produces many vasoactive substances, which may be a cause for secondary hypertension. Early reports suggested the association of myoma and hypertension. We studied the effect of myoma removal on hypertension and erythropoietin level to evaluate this hypothesis.
Patients & Methods:
In this single centered prospective cohort study, in twenty eight patients who were candidates for myomectomy due to myoma, 24 hour holter monitoring of blood pressure and serum erythropoietin were checked before and 6 weeks after hysterectomy.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00898170
|Iran, Islamic Republic of|
|Cardiology Ward Shiraz University of Medical Sciences|
|Shiraz, Fars, Iran, Islamic Republic of, 51318|
|Principal Investigator:||javad kojuri, M.D.||Shiraz University of Medical Sciences|