Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
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Purpose
RATIONALE: Collecting and storing samples of tumor tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help the study of cancer in the future.
PURPOSE: This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer.
| Condition | Intervention |
|---|---|
|
Leukemia Neoplasm of Uncertain Malignant Potential Unspecified Childhood Solid Tumor, Protocol Specific |
Other: cytology specimen collection procedure |
| Study Type: | Observational |
| Official Title: | A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens |
- Repository of malignant, borderline malignant neoplasms, and related biological specimens [ Designated as safety issue: No ]
| Study Start Date: | March 2003 |
OBJECTIVES:
- Collect malignant, borderline malignant neoplasms, and related biological specimens from Children's Oncology Group institutions for cases in which there is no disease-specific biologic protocol.
- Provide a repository for long-term storage of malignant, borderline malignant neoplasms, and related biological specimens from these patients.
- Make specimens available to qualified researchers to understand the biology of cancer in these patients.
OUTLINE: Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future analysis.
PROJECTED ACCRUAL: Not specified.
Eligibility| Ages Eligible for Study: | up to 30 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
Meets any of the following criteria:
- Diagnosed with primary neoplasm
- Developed a second malignant neoplasm
- Any diagnoses having an ICD-O Morphology Code ending in 1, 2, or 3 as listed in the International Classification of Disease for Oncology, Third Edition
Must have biological specimens including solid tumors and leukemias available
Solid tumors meeting the following criteria:
Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed (block or tissue in formalin) primary tumor AND at least 10 unstained paraffin slides for NIH Mandated QC (tumors that have undergone central pathology review are allowed)
- Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
Plueral fluid or cytologic specimens meeting the following criteria:
At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2 unstained smears)
- Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
ALL/AML
- 3-6 mL of bone marrow aspirate and 10 mL of whole blood
- Not eligible for disease-specific biology or banking protocol
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Not specified
Contacts and Locations
Show 176 Study Locations| Study Chair: | Poul Sorensen, MD, PhD | British Columbia Cancer Agency |
More Information
Additional Information:
No publications provided
| ClinicalTrials.gov Identifier: | NCT00898079 History of Changes |
| Obsolete Identifiers: | NCT00228735 |
| Other Study ID Numbers: | CDR0000271415, COG-ABTR01B1 |
| Study First Received: | May 9, 2009 |
| Last Updated: | November 9, 2012 |
| Health Authority: | Unspecified |
Keywords provided by National Cancer Institute (NCI):
|
unspecified childhood solid tumor, protocol specific childhood acute lymphoblastic leukemia childhood acute myeloid leukemia/other myeloid malignancies secondary acute myeloid leukemia acute undifferentiated leukemia mast cell leukemia childhood chronic myelogenous leukemia |
juvenile myelomonocytic leukemia hairy cell leukemia prolymphocytic leukemia T-cell large granular lymphocyte leukemia atypical chronic myeloid leukemia, BCR-ABL1 negative chronic lymphocytic leukemia neoplasm of uncertain malignant potential |
Additional relevant MeSH terms:
|
Neoplasms Leukemia Neoplasms by Histologic Type |
ClinicalTrials.gov processed this record on May 16, 2013