Cardiovascular and Metabolic Responses to a Mixed Meal

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2011 by University of Missouri-Columbia.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University of Missouri-Columbia
ClinicalTrials.gov Identifier:
NCT00882986
First received: April 14, 2009
Last updated: March 30, 2011
Last verified: March 2011
  Purpose

The purpose is to determine whether regular endurance exercise and/or body weight influence the way our nervous and vascular systems respond during the metabolism of meals.


Condition
Insulin Resistance

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Role of Exercise Training and Body Weight on Cardiovascular and Metabolic Responses to a Mixed Meal Tolerance Test

Resource links provided by NLM:


Further study details as provided by University of Missouri-Columbia:

Primary Outcome Measures:
  • insulin/glucose response to mixed meal ingestion [ Time Frame: This study is cross-sectional. Primary and secondary measures will be assessed at a single timepoint. ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • MSNA [ Time Frame: This is a cross-sectional study. Primary and seconardy measures will be assessed at a single visit lasting 4-6 hours. ] [ Designated as safety issue: No ]
  • Blood flow [ Time Frame: This is a cross-sectional study. Primary and seconardy measures will be assessed at a single visit lasting 4-6 hours. ] [ Designated as safety issue: No ]

Estimated Enrollment: 60
Study Start Date: January 2009
Estimated Study Completion Date: February 2012
Estimated Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
fit
2
unfit

  Eligibility

Ages Eligible for Study:   20 Years to 50 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

young, lean, healthy men

Criteria

Inclusion Criteria:

  • healthy, not currently taking any medications

Exclusion Criteria:

  • unhealthy, taking medications
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00882986

Contacts
Contact: John P Thyfault, PhD 573-882-9818 Thyfaultj@missouri.edu

Locations
United States, Missouri
University of Missouri Recruiting
Columbia, Missouri, United States, 65201
Contact: John P Thyfault, PhD    573-882-9818    Thyfaultj@missouri.edu   
Sponsors and Collaborators
University of Missouri-Columbia
Investigators
Principal Investigator: John P Thyfault, PhD University of Missouri-Columbia
  More Information

No publications provided

Responsible Party: Dr. John P. Thyfault Exercise Physiologist, University of Missouri-Columbia
ClinicalTrials.gov Identifier: NCT00882986     History of Changes
Other Study ID Numbers: 1121717
Study First Received: April 14, 2009
Last Updated: March 30, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by University of Missouri-Columbia:
insulin resistance

Additional relevant MeSH terms:
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on July 23, 2014