Long-Term Cardiovascular Risk in Cured Cushing's Patients

This study is currently recruiting participants.

Verified by Massachusetts General Hospital, April 2009

First Received: April 13, 2009 No Changes Posted

Sponsor:	Massachusetts General Hospital
Information provided by:	Massachusetts General Hospital
ClinicalTrials.gov Identifier:	NCT00881283

Purpose

The purpose of this study is to determine whether subjects who have been affected by Cushing's disease in the past maintain some different characteristics compared with subjects who have never been diagnosed with the disease.

Condition
Cushing's Disease

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional
Official Title:	Role of Adipokines in Long-Term Cardiovascular Risk in Cured Cushing's Patients

Resource links provided by NLM:

MedlinePlus related topics: Cushing's Syndrome

U.S. FDA Resources

Further study details as provided by Massachusetts General Hospital:

Biospecimen Retention: Samples With DNA

Biospecimen Description:

serum, urine

Estimated Enrollment:	40
Study Start Date:	October 2008
Estimated Study Completion Date:	October 2009
Estimated Primary Completion Date:	October 2009 (Final data collection date for primary outcome measure)

Groups/Cohorts
cured Cushing's disease

Eligibility

Ages Eligible for Study:	35 Years to 55 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

Cured Cushing's disease

Criteria

Inclusion Criteria:

patients who have been cured of Cushing's disease at least 5 years ago.

Exclusion Criteria:

patients who have been cured of Cushing's disease more than 15 years ago.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00881283

Contacts

Contact: Elena Valassi	617 724 9570	evalassi@partners.org
Contact: Anne Klibanski, MD	617 726 5072	aklibanski@partners.org

Locations

United States, Massachusetts
Neuroendocrine Clinical Center	Recruiting
Boston, Massachusetts, United States, 02114
Contact: Elena Valassi 617-724-9570 evalassi@partners.org
Principal Investigator: Anne Klibanski, MD

Sponsors and Collaborators

Massachusetts General Hospital

Investigators

Principal Investigator:

Anne Klibanski, MD

Massachusetts General Hospital

More Information

No publications provided

Responsible Party:	Massachusetts General Hospital ( Anne Klibanski )
Study ID Numbers:	2008-p-001379
Study First Received:	April 13, 2009
Last Updated:	April 13, 2009
ClinicalTrials.gov Identifier:	NCT00881283 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by Massachusetts General Hospital:

Cushing's disease

Additional relevant MeSH terms:

Pituitary Diseases
Pituitary ACTH Hypersecretion
Hypothalamic Diseases
Hyperpituitarism
Nervous System Diseases
Cushing Syndrome

Central Nervous System Diseases
Endocrine System Diseases
Adrenal Gland Diseases
Brain Diseases
Adrenocortical Hyperfunction

ClinicalTrials.gov processed this record on November 20, 2009