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Copy Number Variations, Inflammatory Cytokines and the Risk of Dementia

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2011 by National Taiwan University Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00878280
First received: August 31, 2008
Last updated: April 21, 2011
Last verified: April 2011
History of Changes
  Purpose

Assess the association of copy number variation (CNV) and inflammatory cytokine with the risk of dementia.


Condition
Dementia

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Copy Number Variations, Expression of Inflammatory Cytokines and the Risk of Dementia - A Two-stage Genome-wide Association Study

Resource links provided by NLM:

MedlinePlus related topics: Dementia
U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • Dementia [ Time Frame: Aug 2008-July 2011 ] [ Designated as safety issue: No ]

Estimated Enrollment: 700
Study Start Date: August 2008
Estimated Study Completion Date: July 2011
Estimated Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
1:control(healthy subjects)
2
2:case(dementia patients)

Detailed Description:

This is a hospital-based case-control study. We plan to assess the association of CNV and inflammatory cytokine with the risk of dementia. Hopefully to find some genetic biomarkers to identify the risk of dementia at an early stage.

  Eligibility

Ages Eligible for Study:   50 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

hospital recruited dementia patients and controls

Criteria

Inclusion Criteria:

  • hospital recruited dementia patients and controls
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00878280

Contacts
Contact: Yen-Ching Chen, ScD 886-2-33668019 chenkaren@yahoo.com

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: yen-ching chen, ScD     3366-8019     chenkaren@yahoo.com    
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: yen-ching chen, ScD National Taiwan University Hospital
  More Information

No publications provided

Responsible Party: Yen-Ching Chen, Institute of Preventive Medicine College of Public Health National Taiwan University
ClinicalTrials.gov Identifier: NCT00878280     History of Changes
Other Study ID Numbers: 200712102R-1
Study First Received: August 31, 2008
Last Updated: April 21, 2011
Health Authority: Taiwan: Department of Health

Additional relevant MeSH terms:
Dementia
Brain Diseases
Central Nervous System Diseases
 Nervous System Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on June 18, 2013