Effect of Rosuvastatin Response in Healthy Subjects: Potential Mechanisms of Anti-inflammatory Effects

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2011 by University of Nebraska.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University of Nebraska
ClinicalTrials.gov Identifier:
NCT00874757
First received: April 1, 2009
Last updated: August 2, 2011
Last verified: August 2011
  Purpose

The purpose of this study is to see whether Statin drugs will act as anti-inflammatories. The investigators will study this potential anti-inflammatory activity in healthy subjects.


Condition
Healthy

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effect of Rosuvastatin Response in Healthy Subjects: Potential Mechanisms of

Resource links provided by NLM:


Further study details as provided by University of Nebraska:

Estimated Enrollment: 20
Study Start Date: July 2009
Estimated Study Completion Date: December 2011
Estimated Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   19 Years to 39 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

20 healthy subjects

Criteria

Inclusion Criteria:

  • Healthy male non-asian subjects

Exclusion Criteria:

  • Patients with increased liver function tests, elevated serum creatinine, patients on anti-inflammatory or immunomodulating drugs
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00874757

Contacts
Contact: Timothy R McGuire, Pharm.D. 402-559-8224 trmcguir@unmc.edu
Contact: Paul Dobesh, Pharm.D. 402-559-1983 pdobesh@unmc.edu

Locations
United States, Nebraska
UNMC College of Pharmacy Recruiting
Omaha, Nebraska, United States, 68198-6045
Contact: Timothy R McGuire, Pharm.D.    402-559-8224    trmcguir@unmc.edu   
Contact: Paul Dobesh, Pharm.D.    402-559-1983    pdobesh@unmc.edu   
Sponsors and Collaborators
University of Nebraska
Investigators
Principal Investigator: Timothy R McGuire, PharmD University of Nebraska
  More Information

No publications provided

Responsible Party: Timothy R. McGuire, University of Nebraska College of Pharmacy
ClinicalTrials.gov Identifier: NCT00874757     History of Changes
Other Study ID Numbers: 088-09
Study First Received: April 1, 2009
Last Updated: August 2, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by University of Nebraska:
Statins, anti-inflammatory
Healthy subjects study

Additional relevant MeSH terms:
Anti-Inflammatory Agents
Rosuvastatin
Therapeutic Uses
Pharmacologic Actions
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Anticholesteremic Agents
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Enzyme Inhibitors
Lipid Regulating Agents

ClinicalTrials.gov processed this record on August 28, 2014