Computer Tomography (CT) Trial of Acute Abdomen (PRACTA)
The purpose of this study is to determine the impact of routinely performed early CT scanning in terms of diagnostic accuracy, patient management and cost-effectiveness compared to current imaging practice in patients suffering from acute abdomen.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Diagnostic
- Diagnostic accuracy [ Time Frame: at discharge and/or 2-3 mo follow-up ] [ Designated as safety issue: No ]
|Study Start Date:||January 2009|
|Study Completion Date:||June 2010|
|Primary Completion Date:||January 2010 (Final data collection date for primary outcome measure)|
Active Comparator: CT
All patients in the CT arm undergo abdominal CT scanning within 24 hours of admission to the ER.
Procedure: Abdominal contrast-enhanced CT scanning
Contrast-enhanced (iohexol 350 mgI/ml, 100 ml IV) CT scanning
No Intervention: Current practice
The patients in the current practice arm are referred to radiological examinations, such as US, plain radiography or CT, based on the clinical need only.