Cue Reactivity in Virtual Reality: The Role of Context

This study has been terminated.
(Slow accrual.)
Sponsor:
Information provided by (Responsible Party):
M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier:
NCT00862927
First received: March 16, 2009
Last updated: June 19, 2012
Last verified: June 2012
  Purpose

The objectives of this proposal are to examine the role of context in a virtual reality (VR) environment and to explore the extent to which cues (i.e., contextual cues or explicit smoking cues) influence craving and physiological arousal within VR.

The current study seeks to determine whether smokers, placed in the context of a VR convenience store devoid of explicit smoking cues, will experience less craving and physiological arousal, compared to exposure to the same VR environment containing explicit smoking cues. This important line of inquiry will help clarify the influence of environmental contexts that may contribute to the overall reactivity effects (e.g., craving, arousal) smokers experience when confronted with cues associated with smoking.


Condition Intervention
Smoking
Other: Breath Sample
Other: Saliva Sample
Behavioral: Questionnaire
Behavioral: View Virtual Reality Scenes

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cue Reactivity in Virtual Reality: The Role of Context

Resource links provided by NLM:


Further study details as provided by M.D. Anderson Cancer Center:

Primary Outcome Measures:
  • Differences in craving and arousal among four scenarios based on repeated survey measure [ Time Frame: Total participation time about 90 minutes; Overall study period (assessment & surveys) approximately 2 years ] [ Designated as safety issue: No ]
    Analyses on craving and arousal measures between-subjects to discern any differences in craving and arousal among the two sets of scenarios. After providing breath and saliva samples, seated participants complete questionnaires and smoke one cigarette to control for variability in time since last cigarette. First 5 questionnaires take approximately 35 minutes to complete, and another, completed after the VR session, approximately 10 minutes.


Enrollment: 21
Study Start Date: March 2009
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Cue reactivity in virtual reality
Breath Scan + Saliva Sample + Questionnaires + View Virtual Reality Scenes
Other: Breath Sample
Breathe into machine measuring carbon monoxide.
Other: Saliva Sample
Chew cotton ball for 30 seconds for cotinine measurement.
Behavioral: Questionnaire
6 surveys, taking approximately 30 minutes total.
Behavioral: View Virtual Reality Scenes
Use virtual reality helmet and hand-held controller to answer questions about 4 viewing scenes while wearing physiological measurement skin sensors, approximately 6 minutes.
Other Name: VR

  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Smokers, 18 years of age or older.

Criteria

Inclusion Criteria:

  1. At least 18 years old
  2. Self-report of smoking at least 10 cigarettes per day
  3. Expired carbon monoxide (CO) equal to or greater than 10 ppm
  4. English speaking and able to read at > 6th grade level
  5. Not interested in quitting smoking in next 30 days

Exclusion Criteria:

1) Self-report history of motion sickness or vertigo

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00862927

Locations
United States, Texas
UT MD Anderson Cancer Center
Houston, Texas, United States, 77030
Sponsors and Collaborators
M.D. Anderson Cancer Center
Investigators
Principal Investigator: Brian L. Carter, PhD UT MD Anderson Cancer Center
  More Information

Additional Information:
No publications provided

Responsible Party: M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier: NCT00862927     History of Changes
Other Study ID Numbers: 2008-0544
Study First Received: March 16, 2009
Last Updated: June 19, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by M.D. Anderson Cancer Center:
Smoking Cessation
Cigarette Smoking
Tobacco Smoking
Cue Reactivity
Virtual Reality
VR
Contextual Cues
Explicit Smoking Cues
Craving
Physiological Arousal
Nicotine Dependence
Breath Sample
Saliva Test
Questionnaire

ClinicalTrials.gov processed this record on September 18, 2014