Trial record 4 of 524 for:    Open Studies | "Tomography, X-Ray Computed"

4D PET/CT Imaging in Lung and Colorectal Cancer With Liver Metastasis

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2014 by M.D. Anderson Cancer Center
Sponsor:
Collaborator:
GE Healthcare
Information provided by (Responsible Party):
M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier:
NCT00862680
First received: March 16, 2009
Last updated: April 3, 2014
Last verified: April 2014
  Purpose

The goal of this clinical research study is to learn if adjusting the PET/CT scanner to allow for breathing motion can improve the quality of PET/CT images.


Condition Intervention
Colorectal Cancer
Lung Cancer
Liver Cancer
Procedure: PET/CT Scan

Study Type: Interventional
Study Design: Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: 4D PET/CT Imaging in Lung and Colorectal Cancer With Liver Metastasis

Resource links provided by NLM:


Further study details as provided by M.D. Anderson Cancer Center:

Primary Outcome Measures:
  • Learn if adjusting the PET/CT scanner to allow for breathing motion can improve the quality of PET/CT images. [ Time Frame: 2 Years ] [ Designated as safety issue: No ]

Estimated Enrollment: 75
Study Start Date: March 2009
Estimated Primary Completion Date: March 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: PET/CT Scan
Routine PET/CT scan with small plastic box (weighing less than 1 oz) placed on abdominal area to track breathing motion.
Procedure: PET/CT Scan
Routine PET/CT scan with small plastic box (weighing less than 1 oz) placed on abdominal area to track breathing motion.
Other Names:
  • 4D Positron Emission Tomography/Computed Tomography
  • PET/CT Imaging

Detailed Description:

Routine PET/CT scans are taken while patients are breathing normally. The motions made by breathing can reduce the image quality of the scan. Minimizing the effects of this motion by taking the images and processing the scans differently may improve the image quality.

The PET/CT Scan:

If you agree to take part in this study, a small plastic box (weighing less than 1 ounce) will be placed on your abdominal area before your routine PET/CT scan. This box is used to track your breathing motion. This information will be used to help process the scan.

Your PET/CT scan will be performed as usual. During the scan, the researchers will focus on your lower chest/upper abdomen (areas that experience breathing motion). Having to focus on this area might extend the scan by up to 12 minutes.

Length of Study:

Your participation on this study will be complete when your scheduled PET/CT scan is complete.

This is an investigational study. The imaging focused on your lower chest/upper abdomen during the scan is investigational.

Up to 75 patients will take part in this study. All will be enrolled at MD Anderson.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  1. Patients with suspected colorectal cancer with nodules in the lung or liver (1-2 cm in diameter) will be eligible for this study.
  2. Patients with suspected lung cancer with nodules in the lung or liver (1-2 cm in diameter) will be eligible for this study.

Exclusion Criteria:

  1. Pediatric patients (younger than 18 years) will be excluded.
  2. Patients that cannot tolerate being scanned for an additional 12 minutes with arms above their head will be excluded.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00862680

Contacts
Contact: Osama R. Mawlawi, PhD 713-563-2711

Locations
United States, Texas
UT MD Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Principal Investigator: Osama R. Mawlawi, PhD         
Sponsors and Collaborators
M.D. Anderson Cancer Center
GE Healthcare
Investigators
Principal Investigator: Osama R. Mawlawi, PhD UT MD Anderson Cancer Center
  More Information

Additional Information:
No publications provided

Responsible Party: M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier: NCT00862680     History of Changes
Other Study ID Numbers: 2008-0853, NCI-2011-00528
Study First Received: March 16, 2009
Last Updated: April 3, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by M.D. Anderson Cancer Center:
Lung Colorectum
Colorectal cancer
Lung Cancer
Liver Cancer
Non-small cell lung cancer
NSCLC
4D PET/CT Imaging
Positron emission tomography/computed tomography
PET/CT scan
Breathing motion

Additional relevant MeSH terms:
Colorectal Neoplasms
Liver Neoplasms
Lung Neoplasms
Neoplasm Metastasis
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Neoplasms
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases
Liver Diseases
Respiratory Tract Neoplasms
Thoracic Neoplasms
Lung Diseases
Respiratory Tract Diseases
Neoplastic Processes
Pathologic Processes

ClinicalTrials.gov processed this record on July 24, 2014