Lung Transplantation in Respiratory Failure Patients

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2009 by National Taiwan University Hospital.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00854165
First received: March 1, 2009
Last updated: March 2, 2009
Last verified: March 2009
  Purpose

Survival after cadaveric lung transplantation in recipients depended on ventilation support prior to transplantation has been reported to have relative high surgical mortality and morbidity rate. The objectives of this study were to describe the short-term outcomes of bilateral sequential lung transplantation under extracorporeal membrane oxygenation (ECMO) support in a consecutive series of patients who depended on noninvasive and invasive ventilation support preoperatively .


Condition
Respiratory Failure

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Extracorporeal Membrane Oxygenation Support for Bilateral Sequential Lung Transplantation in Respiratory Failure Patients.

Resource links provided by NLM:


Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • 6 months and one year survival after lung transplatn. [ Time Frame: 6 months and one year posttransplant ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Pulmonary function results, at baseline and posttransplant 1, 3, and 6 months. [ Time Frame: baseline, post-op 1,3, and 6 months ] [ Designated as safety issue: No ]

Enrollment: 10
Study Start Date: February 2009
Estimated Study Completion Date: June 2009
Estimated Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)
Detailed Description:

The one-year survival rate and postoperative pulmonary functional results will be reported in this study.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Between July 2006 and July 2008, we performed bilateral sequential lung transplantation under venoarterious ECMO support in 10 respiratory failure patients with various lung diseases. This study wanted to report the preoperative condition, postoperative complications, and short-term outcome after lung transplantation.

Criteria

Inclusion Criteria:

  • respiratory patients depended on ventilator supports prior to lung transplant

Exclusion Criteria:

  • non-cardaveric lung transplant
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00854165

Locations
Taiwan
Department of Surgery, National Taiwan University Hospital
Taipei, Taiwan, 100
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Study Director: Yung-Chie Lee, MD, PhD Department of Surgery, National Taiwan University Hospital
Principal Investigator: Hsao-Hsun Hsu, MD Department of Surgery, National Taiwan University Hospital
  More Information

No publications provided

Responsible Party: Yung-Chie Lee, Department of Surgery
ClinicalTrials.gov Identifier: NCT00854165     History of Changes
Other Study ID Numbers: 200901015R
Study First Received: March 1, 2009
Last Updated: March 2, 2009
Health Authority: Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:
lung transplantation
respiratory failure
ECMO
Lung transplants in respiratory failure patients

Additional relevant MeSH terms:
Respiratory Insufficiency
Respiration Disorders
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on August 18, 2014