Post-Operative Treatment With Ketorolac After Abdominal Myomectomy

This study has been completed.
New York Presbyterian Hospital
Mount Sinai School of Medicine
Information provided by:
Ascher-Walsh, Charles, M.D. Identifier:
First received: February 14, 2009
Last updated: February 17, 2009
Last verified: February 2009

The purpose of this study is to determine if ketorolac, given after abdominal myomectomy, will decrease the frequency of post-oerative fevers as well as improve post-operative pain management.

Condition Intervention
Febrile Morbidity
Drug: ketorolac
Drug: saline

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Caregiver)
Primary Purpose: Treatment
Official Title: Effects of Ketorolac on Post-Operative Febrile Morbidity and Pain Management in Abdominal Myomectomy Patients

Resource links provided by NLM:

Further study details as provided by Ascher-Walsh, Charles, M.D.:

Primary Outcome Measures:
  • Post-operative febrile morbidity [ Time Frame: Inital 24hrs post-operative ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Post-operative pain management [ Time Frame: Initial 24hrs post-operative ]

Enrollment: 112
Study Start Date: September 1999
Study Completion Date: August 2001
Primary Completion Date: August 2001 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Placebo Comparator: 1
Drug: saline
15mg IV every 6hrs for 4 doses
Active Comparator: 2
Drug: ketorolac
15mg IV every6 hours for 4doses
Other Name: Toradol


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Ant patient undregoing abdominal myomectomy

Exclusion Criteria:

  • Patients with contraindication to NSAIDs including history of peptic ulcer disease, renal disease, bleeding diathesis, or hypersensitivity to NSAIDS
  Contacts and Locations
Please refer to this study by its identifier: NCT00845754

United States, New York
Columbia University Medical Center
New York, New York, United States, 10032
Sponsors and Collaborators
Ascher-Walsh, Charles, M.D.
New York Presbyterian Hospital
Mount Sinai School of Medicine
  More Information

No publications provided

Responsible Party: Charles Ascher-Walsh MD, Mount Sinai School of Medicine Identifier: NCT00845754     History of Changes
Other Study ID Numbers: ASW 124
Study First Received: February 14, 2009
Last Updated: February 17, 2009
Health Authority: United States: Institutional Review Board

Keywords provided by Ascher-Walsh, Charles, M.D.:
Post-operative febrile morbidity
Post-operative pain management

Additional relevant MeSH terms:
Body Temperature Changes
Signs and Symptoms
Ketorolac Tromethamine
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Pharmacologic Actions
Anti-Inflammatory Agents
Therapeutic Uses
Antirheumatic Agents
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Central Nervous System Agents processed this record on April 21, 2014