Pharmaceutical Care and Clinical Outcomes for the Elderly Taking Potentially Inappropriate Medication

This study is enrolling participants by invitation only.
Information provided by:
Shin Kong Wu Ho-Su Memorial Hospital Identifier:
First received: February 12, 2009
Last updated: March 30, 2009
Last verified: March 2009

The investigators propose that clinical pharmacist interventions would reduce the rate of adverse drug events in elderly patients taking potentially inappropriate medication.

Condition Intervention
Chronic Disease
Behavioral: Pharmacist intervention

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Caregiver, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Pharmaceutical Care and Clinical Outcomes for the Elderly Taking Potentially Inappropriate Medication: a Randomized-Controlled Trial

Resource links provided by NLM:

Further study details as provided by Shin Kong Wu Ho-Su Memorial Hospital:

Primary Outcome Measures:
  • Number of unsolved drug-related problems [ Time Frame: 14 days after randomization ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Rate of adverse drug event during hospitalization [ Time Frame: 14 days after randomization ] [ Designated as safety issue: No ]
  • Number of potentially inappropriate medication [ Time Frame: 14 days after randomization ] [ Designated as safety issue: No ]

Estimated Enrollment: 120
Study Start Date: February 2009
Estimated Study Completion Date: February 2010
Estimated Primary Completion Date: February 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Pharmacist intervention
Patients in the intervention group will receive pharmaceutical care delivered by clinical pharmacist, which including medication review, medication reconciliation, patient education and recommended actions.
Behavioral: Pharmacist intervention
Medication review, medication reconciliation, and pharmacotherapy recommendation.
No Intervention: Usual care
Patients randomized to usual care group will receive routine review of medication by ward-based pharmacist and nurse.


Ages Eligible for Study:   65 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Hospitalized patients aged at least 65 years
  • Taking at least six prescribed medicines regularly, including at least one potential inappropriate medication

Exclusion Criteria:

  • Patients who refused informed consent
  • Discharged before consent could be obtained
  • Cognitive impaired
  Contacts and Locations
Please refer to this study by its identifier: NCT00844025

Shin Kong Wo Ho-Su Memorial Hospital, Department of Pharmacy
Taipei, Taiwan, 111
Sponsors and Collaborators
Shin Kong Wu Ho-Su Memorial Hospital
Principal Investigator: Liu Jen Wei, MS Shin Kong Wo Ho-Su Memorial Hospital
  More Information

Responsible Party: Tsai Ming Dar/Chief of Shin Kong Wu Ho-Su Memorial Hospital Research and Education Assessment Department, Shin Kong Wu Ho-Su Memorial Hospital Identifier: NCT00844025     History of Changes
Other Study ID Numbers: SKH-8302-98-NDR-05
Study First Received: February 12, 2009
Last Updated: March 30, 2009
Health Authority: Taiwan: Department of Health

Keywords provided by Shin Kong Wu Ho-Su Memorial Hospital:
Adverse drug reaction
Inappropriate medication
Pharmaceutical care

Additional relevant MeSH terms:
Chronic Disease
Disease Attributes
Pathologic Processes processed this record on April 17, 2014