Impact of Predicting Anti-Angiogenic Response in mRCC Using Functional Imaging (REMISCAN)
Recruitment status was Recruiting
The goal is to study the impact of functional MRI and CT evaluation of changes in tumor vessels induced by anti-angiogenic treatment in patients with metastatic RCC.
The hypothesis is that good responders and poor responders will have different responses induced by anti-angiogenic treatment, and that the detection of theses changes by functional imaging can improve the therapeutic management.
Functional CT and MRI will be performed in 200 patients before the beginning of antiangiogenic treatment, 7 days after and every 6 week until tumor progression (as defined by the RECIST criteria). Perfusion and diffusion parameters will be measured using a dedicated software.
Carcinoma, Renal Cell
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Medical and Economical Impact of Predicting the Response to Anti-Angiogenic Treatment in Metastatic Renal Cell Carcinoma Using Functional CT and MRI|
|Study Start Date:||September 2008|
|Estimated Study Completion Date:||August 2012|
|Estimated Primary Completion Date:||September 2010 (Final data collection date for primary outcome measure)|
|Contact: Cuenod MD, Charles André, PhD||+331 56 09 27 firstname.lastname@example.org|
|service of oncology- HEGP||Recruiting|
|Paris, France, 75015|
|Contact: OUDARD Stephane, PhD|
|Principal Investigator: OUDARD Stephane, PHD|
|Principal Investigator:||Stephane OUDART, PhD||Assistance Publique - Hôpitaux de Paris|