Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer
The purpose of this study is to determine the difference of skin carotenoid levels between subjects with previous squamous cell carcinomas (SCC), subjects with previous basal cell carcinomas (BCC) and a control group.
Basal Cell Carcinoma
Squamous Cell Carcinoma
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
|Official Title:||Comparison of Skin Carotenoid Levels Between Subjects With History of Cutaneous Squamous Cell Carcinoma and Subjects With History of Basal Cell Carcinoma Versus a Control Group|
- Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Control Subjects [ Time Frame: baseline ] [ Designated as safety issue: No ]Mean carotenoid levels in subjects with a history of squamous cell carcinoma were compared to mean carotenoid levels in control subjects without a history of nonmelanoma skin cancer.
- Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Subjects With History of Basal Cell Carcinoma [ Time Frame: baseline ] [ Designated as safety issue: No ]
- Skin Carotenoid Levels in Subjects With History of Basal Cell Carcinoma Versus Control Group [ Time Frame: baseline ] [ Designated as safety issue: No ]
|Study Start Date:||February 2009|
|Study Completion Date:||January 2012|
|Primary Completion Date:||January 2012 (Final data collection date for primary outcome measure)|
Previous history of SCC
Participants had previous history of SCC
Previous history of BCC
Participants had previous history of BCC
Participants had no previous history of squamous cell carcinoma or basal cell carcinoma
There has been experimental and clinical research evaluating association of different carotenoids and incidence of malignancies, including Non- Melanoma Skin Cancer (NMSC). An easy and inexpensive way to determine which subjects would benefit from supplementation with carotenoids or retinoids could be the measurement of skin carotenoid levels.The least invasive way to perform it is through Raman spectroscopy which is a technique that uses a laser light that can be used to quantify carotenoids on the skin. We will compare the skin carotenoid levels of subjects with previous history of SCC or BCC and subjects without history of previous NMSC.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00836342
|United States, Massachusetts|
|Clinical Unit for Research Trials in Skin - MGH|
|Boston, Massachusetts, United States, 02114|
|Principal Investigator:||Alexandra B Kimball, MD, MPH||Massachusetts General Hospital|