Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic (BIO-IRA)

This study has been completed.
Sponsor:
Collaborator:
Regional Clinical Research
Information provided by:
University Hospital, Grenoble
ClinicalTrials.gov Identifier:
NCT00835809
First received: February 3, 2009
Last updated: September 6, 2010
Last verified: September 2010
  Purpose

Biomarkers have an interest in clinic diagnostic ,therapeutic and prognosis in pathophysiologic situation including cardiovascular.But interest of biomarkers in diagnostic care of severe acute respiratory insufficiency remains to clear.

We propose to determine the more relevant marker combination in this case.


Condition
Acute Respiratory Insufficiency

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Multi Marker Approach Interest in Emergency in Acute Respiratory Insufficiency Diagnostic

Resource links provided by NLM:


Further study details as provided by University Hospital, Grenoble:

Biospecimen Retention:   Samples With DNA

Protein sample


Enrollment: 400
Study Start Date: October 2008
Study Completion Date: October 2009
Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
Acute respiratory diseases.
Patient admit in emergency or intensive care unite with acute respiratory insufficiency.

Detailed Description:

In urgence of a severe acute respiratory insufficiency,for thanks to an approach diagnostic, therapeutic and prognostic we propose to determine the more relevant biomarker combination.

An expert committee will compare the biomarker diagnostic and prognostic relevance thanks to all elements clinico-biological and patient monitoring.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Emergency and unit intensive care patient.

Criteria

Inclusion Criteria:

  • Oxygen saturation below or equal to 92% in ambient air.
  • Respiratory frequence above 25 cycle per minute

Exclusion Criteria:

  • Minors
  • Pregnant or lactating women
  • Patient without social security
  • Patient hospitalize without consent
  • Chest pain with acute coronary electro-cardiographic change leading immediate achievement of a diagnostic coronary angiography and/or therapeutic
  • Pneumothorax
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00835809

Locations
France
University Hospital Grenoble
Grenoble, France, 38000
Sponsors and Collaborators
University Hospital, Grenoble
Regional Clinical Research
Investigators
Principal Investigator: ARA SOMOHANO Claire, PH Emergency
  More Information

No publications provided

Responsible Party: Ms Claire ARA SOMOHANO, Service de réanimation médicale
ClinicalTrials.gov Identifier: NCT00835809     History of Changes
Other Study ID Numbers: 0811, 2008-A00703-52
Study First Received: February 3, 2009
Last Updated: September 6, 2010
Health Authority: France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)

Keywords provided by University Hospital, Grenoble:
Acute respiratory insufficiency respiratory
Biomarkers
Emergency
Intensive care unit
Prospective
Patient hospitalize in emergency or in intensive care unit
for acute respiratory insufficiency

Additional relevant MeSH terms:
Emergencies
Respiratory Insufficiency
Disease Attributes
Pathologic Processes
Respiration Disorders
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on September 16, 2014