Screening Scottish Swimmers for Asthma and Rhinitis (CLE004)

This study has been completed.
Sponsor:
Information provided by:
University of Dundee
ClinicalTrials.gov Identifier:
NCT00831428
First received: January 28, 2009
Last updated: August 11, 2011
Last verified: May 2009
  Purpose

The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.


Condition Intervention
Asthma
Rhinitis
Other: no intervention

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: A Pilot Study to Identify the Prevalence of Exercise- Induced Asthma and Rhinitis in Scottish Swimmers, Using Mannitol Challenge as a Screening Tool.

Resource links provided by NLM:


Further study details as provided by University of Dundee:

Primary Outcome Measures:
  • Tidal Nitric Oxide [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Mannitol Challenge [ Time Frame: This test will be performed once on a district and once on a national squad training day ] [ Designated as safety issue: No ]
  • Sport-based Challenge [ Time Frame: This test will be performed once on a district and once on a national squad training day ] [ Designated as safety issue: No ]
  • Nasal Nitric Oxide [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ] [ Designated as safety issue: No ]
  • Skin Prick Test [ Time Frame: This test will be performed once on a district and once on a national squad training day ] [ Designated as safety issue: No ]
  • Mini Nasal Lavage [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ] [ Designated as safety issue: No ]

Enrollment: 97
Study Start Date: February 2009
Study Completion Date: June 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Scottish swimming team Other: no intervention
this is a screening study, not an interventional study

  Eligibility

Ages Eligible for Study:   11 Years to 23 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

The Scottish national and district swimming teams

Criteria

Inclusion Criteria:

  • member of the Scottish national and district swimming team
  • informed consent obtained

Exclusion Criteria:

  • pregnant, lactating or planning to become pregnant
  • concomitant use of medicines (prescribed, over-the-counter or herbal) that may interfere with the trial.
  • any clinically significant medical condition, as deemed by the clinical investigators, which may endanger the health of the participant or jeopardise the protocol.
  • inability to comply with the protocol.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00831428

Locations
United Kingdom
The national swimming academy in Stirling
Stirling, Stirlingshire, United Kingdom, FK9 4LA
Sponsors and Collaborators
University of Dundee
Investigators
Principal Investigator: Karine L Clearie, MBBS, MRCP Asthma and Allergy Research Group
Study Director: Brian J Lipworth, MBchB Asthma and Allergy Research Group
  More Information

No publications provided

Responsible Party: Dr Karine Clearie, Asthma and Allergy Research Group
ClinicalTrials.gov Identifier: NCT00831428     History of Changes
Other Study ID Numbers: CLE004
Study First Received: January 28, 2009
Results First Received: August 11, 2011
Last Updated: August 11, 2011
Health Authority: United Kingdom: Research Ethics Committee

Keywords provided by University of Dundee:
asthma
rhinitis
swimmers
mannitol

Additional relevant MeSH terms:
Asthma
Rhinitis
Bronchial Diseases
Hypersensitivity
Hypersensitivity, Immediate
Immune System Diseases
Lung Diseases
Lung Diseases, Obstructive
Nose Diseases
Otorhinolaryngologic Diseases
Respiratory Hypersensitivity
Respiratory Tract Diseases
Respiratory Tract Infections

ClinicalTrials.gov processed this record on October 20, 2014