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Trial record 13 of 32 for:    "Asthma, Exercise-Induced"
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Prevalence of Exercise-Induced Asthma in Select Cohorts of College Athletes

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Jonathan Parsons, Ohio State University
ClinicalTrials.gov Identifier:
NCT00806000
First received: December 9, 2008
Last updated: October 9, 2012
Last verified: October 2012
History of Changes
  Purpose

This study is investigating how commonly exercise-induced asthma happens in athletes and the best way to diagnose exercise-induced asthma. Exercise-induced asthma describes narrowing of the airways in the lungs that occurs in certain people when they exercise. This can cause shortness of breath, cough, and fatigue during exercise and can impair athletic performance. Exercise-induced asthma can be difficult to diagnose. This is a research study, because the investigators are examining the best way to document a diagnosis of exercise-induced asthma. The investigators are also interested in examining why exercise-induced asthma may occur.


Condition
Asthma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Prevalence of Exercise-Induced Asthma in Select Cohorts of College Athletes

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Ohio State University:

Secondary Outcome Measures:
  • To identify characteristics of athletes that may be associated with increased relative risk for asthma To identify characteristics of athletes that may be associated with increased relative risk for asthma. To identify characteristics of athletes tha [ Time Frame: end of study ] [ Designated as safety issue: No ]

Enrollment: 150
Study Start Date: December 2008
Study Completion Date: December 2010
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)

Detailed Description:

prospective, cohort study of the prevalence of asthma in select athletic teams at a large, collegiate athletic program as documented by self-report versus lung function testing. Athletes from men's and women's ice hockey, soccer, and lacrosse will be studied. Each athlete will indicate via self-report on questionnaires whether they have asthma, and then subsequently will be tested utilizing specialized lung function testing. These teams were chosen, because it will allow for gender-matching across teams and they had subjectively reported asthma prevalence rates based on prior pilot data.

Inclusion Criteria:

  1. Varsity athlete on athletic team of interest here at The Ohio State University
  2. 18 years of age or older
  3. No short-acting bronchodilator use for 6 hours prior to testing
  4. No long-acting bronchodilator use for 36 hours prior to testing
  5. No inhaled corticosteroids or leukotriene modifiers for 72 hours prior to testing
  6. Non-smoker for 6 months or longer
  7. Less than 10 pack year (number of packs per day (x) years of smoking=pack years) smoking history, as smoking causes chronic changes in the profile of inflammatory cells of lungs and also makes airways more likely to spasm. This is true even for non-smokers.

Exclusion criteria:

  1. pregnancy
  2. recent upper respiratory tract infection (within 2 weeks of study enrollment)
  3. Objective evidence of severe lung impairment on pulmonary testing performed at the beginning of the study.
  4. Participation in another interventional research trial
  5. Unable to provide consent
  6. Asthma exacerbation within the last 4 weeks
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

select athletic teams including men and women's ice hockey, soccer, and lacross

Criteria

Inclusion Criteria:

  • Varsity athlete on athletic team of interest here at The Ohio State University
  • 18 years of age or older
  • No short-acting bronchodilator use for 6 hours prior to testing
  • No long-acting bronchodilator use for 36 hours prior to testing
  • No inhaled corticosteroids or leukotriene modifiers for 72 hours prior to testing
  • Non-smoker for 6 months or longer
  • Less than 10 pack year (number of packs per day (x) years of smoking=pack years) smoking history, as smoking causes chronic changes in the profile of inflammatory cells of lungs and also makes airways more likely to spasm. This is true even for non-smokers

Exclusion Criteria:

  • pregnancy
  • recent upper respiratory tract infection (within 2 weeks of study enrollment)
  • Objective evidence of severe lung impairment on pulmonary testing performed at the beginning of the study.
  • Participation in another interventional research trial
  • Unable to provide consent
  • Asthma exacerbation within the last 4 weeks
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00806000

Locations
United States, Ohio
The Ohio State University
Columbus, Ohio, United States, 43210
Sponsors and Collaborators
Ohio State University
Investigators
Principal Investigator: Jonathan P Parsons, MD Ohio State University
  More Information

No publications provided

Responsible Party: Jonathan Parsons, M.D., Ohio State University
ClinicalTrials.gov Identifier: NCT00806000     History of Changes
Other Study ID Numbers: 2008H0094
Study First Received: December 9, 2008
Last Updated: October 9, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Ohio State University:
Prevalence of Exercised induced asthma in athletes

Additional relevant MeSH terms:
Asthma
Asthma, Exercise-Induced
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
 Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases

ClinicalTrials.gov processed this record on May 21, 2013