Walking, Spontaneous Physical Activity and Lipid Oxidation After Dietary Treatment of Obesity

The recruitment status of this study is unknown because the information has not been verified recently.

Verified October 2008 by University Hospital, Tours.
Recruitment status was Recruiting

Sponsor:

Information provided by:

University Hospital, Tours

ClinicalTrials.gov Identifier:

NCT00775970

First received: October 17, 2008

Last updated: NA

Last verified: October 2008

History: No changes posted

Purpose

The purpose of this study is to determine whether walking exercise after dietary treatment of obesity is associated with a decrease of the daily spontaneous physical activity and\or with an increase of the time spent in sedentary activities. Our hypothesis is that the practice of walking as an exercise during the phase of weight stability following the dietary treatment of obesity leads to a reduction of spontaneous physical activity and\or to an increase in the time spent in sedentary activities.

Condition	Intervention
Obesity	Behavioral: walking activity

Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Blind (Subject) Primary Purpose: Basic Science
Official Title:	Influence of Walking on Spontaneous Physical Activity and on Lipid Oxidation Following Dietary Treatment of Obesity

Resource links provided by NLM:

MedlinePlus related topics: Obesity

U.S. FDA Resources

Further study details as provided by University Hospital, Tours:

Primary Outcome Measures:

Daily time of moderate physical activity, inactivity and total physical activity measured by a portable monitor of physical activity [ Time Frame: 10 weeks ]

Secondary Outcome Measures:

Daily energy expenditure and respiratory quotient during a stay in a respiration chamber [ Time Frame: 10 weeks ]

Estimated Enrollment:	20
Study Start Date:	May 2008

Detailed Description:

The subjects of this study will be randomised in 2 groups:

A group with usual follow-up and a group with usual follow-up associated with recommendations to introduce a program of walking achieving gradually 2000-2500 kcal/week.

Eligibility

Ages Eligible for Study:	18 Years to 50 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Women from 18 to 50 year-old
In phase of weight stability
BMI<40kg/m²

Exclusion Criteria:

History of bariatric surgery
Diabetes
Suspicion of obstructive sleep apnea syndrome

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00775970

Contacts

Contact: David JACOBI, MD	+33247474727	jacobi@med.univ-tours.fr
Contact: Pascaline RAMEAU, CRA	+33247366249	rameau@med.univ-tours.fr

Locations

France
Service de Médecine Interne - Nutrition / CHRU de Tours	Recruiting
Tours, France, 37044
Contact: David JACOBI, MD +33247472269 jacobi@med.univ-tours.fr
Principal Investigator: David JACOBI, MD
Sub-Investigator: Charles COUET, PhD

Sponsors and Collaborators

University Hospital, Tours

Investigators

Principal Investigator:

David JACOBI, MD

Service de médecine Interne-Nutrition

More Information

Publications:

Brage S, Brage N, Franks PW, Ekelund U, Wong MY, Andersen LB, Froberg K, Wareham NJ. Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure. J Appl Physiol. 2004 Jan;96(1):343-51. Epub 2003 Sep 12.

Fogelholm M, Kukkonen-Harjula K. Does physical activity prevent weight gain--a systematic review. Obes Rev. 2000 Oct;1(2):95-111. Review.

Froidevaux F, Schutz Y, Christin L, Jéquier E. Energy expenditure in obese women before and during weight loss, after refeeding, and in the weight-relapse period. Am J Clin Nutr. 1993 Jan;57(1):35-42.

Jéquier E, Schutz Y. Long-term measurements of energy expenditure in humans using a respiration chamber. Am J Clin Nutr. 1983 Dec;38(6):989-98.

Kraemer WJ, Volek JS, Clark KL, Gordon SE, Incledon T, Puhl SM, Triplett-McBride NT, McBride JM, Putukian M, Sebastianelli WJ. Physiological adaptations to a weight-loss dietary regimen and exercise programs in women. J Appl Physiol. 1997 Jul;83(1):270-9.

Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science. 1999 Jan 8;283(5399):212-4.

Levine JA, Schleusner SJ, Jensen MD. Energy expenditure of nonexercise activity. Am J Clin Nutr. 2000 Dec;72(6):1451-4.

Nicklas BJ, Rogus EM, Goldberg AP. Exercise blunts declines in lipolysis and fat oxidation after dietary-induced weight loss in obese older women. Am J Physiol. 1997 Jul;273(1 Pt 1):E149-55.

van Aggel-Leijssen DP, Saris WH, Hul GB, van Baak MA. Short-term effects of weight loss with or without low-intensity exercise training on fat metabolism in obese men. Am J Clin Nutr. 2001 Mar;73(3):523-31.

van Aggel-Leijssen DP, Saris WH, Wagenmakers AJ, Hul GB, van Baak MA. The effect of low-intensity exercise training on fat metabolism of obese women. Obes Res. 2001 Feb;9(2):86-96.

Zurlo F, Lillioja S, Esposito-Del Puente A, Nyomba BL, Raz I, Saad MF, Swinburn BA, Knowler WC, Bogardus C, Ravussin E. Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. Am J Physiol. 1990 Nov;259(5 Pt 1):E650-7.

Responsible Party:	University Hospital, Tours
ClinicalTrials.gov Identifier:	NCT00775970 History of Changes
Other Study ID Numbers:	PHRI07-DJ APS
Study First Received:	October 17, 2008
Last Updated:	October 17, 2008
Health Authority:	France: Ministry of Health

Keywords provided by University Hospital, Tours:

Obesity
Weight loss maintenance
Spontaneous physical activity
Lipid oxydation
Walking

Additional relevant MeSH terms:

Obesity
Overnutrition
Nutrition Disorders

Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on May 22, 2013

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