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Treatment for Word Retrieval Impairments in Aphasia

This study is currently recruiting participants.
Verified May 2012 by Old Dominion University
Sponsor:
Collaborator:
National Institute on Deafness and Other Communication Disorders (NIDCD)
Information provided by (Responsible Party):
Dr. Anastasia Raymer, Old Dominion University
ClinicalTrials.gov Identifier:
NCT00764400
First received: September 30, 2008
Last updated: May 18, 2012
Last verified: May 2012
History of Changes
  Purpose

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.


Condition Intervention Phase
Stroke
 Behavioral: Word Retrieval Treatments for Aphasia
 Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Official Title: Communication Outcomes for Naming Treatments in Aphasia

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Old Dominion University:

Primary Outcome Measures:
  • Daily Probe Picture Naming [ Time Frame: daily probes from three times per week for up to 3 months and one month posttreatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Western Aphasia Battery [ Time Frame: pre-treatment and at treatment completion ] [ Designated as safety issue: No ]
  • Boston Naming Test [ Time Frame: pretreatment and at treatment completion ] [ Designated as safety issue: No ]
  • Discourse Sample [ Time Frame: pre-treatment and at treatment completion ] [ Designated as safety issue: No ]

Estimated Enrollment: 16
Study Start Date: August 2008
Estimated Study Completion Date: July 2012
Estimated Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Errorless Naming Treatment Behavioral: Word Retrieval Treatments for Aphasia
Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.
Experimental: Verbal+Gestural Facilitation Behavioral: Word Retrieval Treatments for Aphasia
Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

  Eligibility

Ages Eligible for Study:   21 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • left hemisphere stroke >4 months earlier
  • aphasia with word retrieval impairments
  • >21 years of age right handed
  • speaker of English as the preferred language
  • >6 grade education

Exclusion Criteria:

  • history of developmental learning difficulties
  • history of prior neurological illnesses
  • chronic medical illnesses that restrict participation in speech therapy
  • alcohol or drug dependence
  • severe uncorrected impairments of vision or hearing
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00764400

Contacts
Contact: Anastasia M Raymer, PhD 757-683-4522 sraymer@odu.edu
Contact: Sheryl Spence 757-683-4117

Locations
United States, Virginia
Old Dominion University Speech and Hearing Clinic Recruiting
Norfolk, Virginia, United States, 23529
Contact: Anastasia M Raymer, PhD     757-683-4522     sraymer@odu.edu    
Principal Investigator: Anastasia Raymer, PhD            
Sponsors and Collaborators
Old Dominion University
National Institute on Deafness and Other Communication Disorders (NIDCD)
Investigators
Principal Investigator: Anastasia M Raymer, PhD Old Dominion University
  More Information

No publications provided

Responsible Party: Dr. Anastasia Raymer, Professor of Communications Disorders & Special Education, Old Dominion University
ClinicalTrials.gov Identifier: NCT00764400     History of Changes
Other Study ID Numbers: R15 DC009690, 3R15DC009690, R15 DC009690
Study First Received: September 30, 2008
Last Updated: May 18, 2012
Health Authority: United States: Federal Government

Keywords provided by Old Dominion University:
aphasia
anomia
speech therapy
rehabilitation

Additional relevant MeSH terms:
Language Disorders
Aphasia
Stroke
Speech Disorders
Communication Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
 Nervous System Diseases
Signs and Symptoms
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on May 16, 2013