Treatment for Word Retrieval Impairments in Aphasia - Full Text View

Sponsor:	National Institute on Deafness and Other Communication Disorders (NIDCD)
Information provided by:	National Institute on Deafness and Other Communication Disorders (NIDCD)
ClinicalTrials.gov Identifier:	NCT00764400

Purpose

In this study we are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment we will administer several tests and conversational samples to examine changes associated with the treatments. We hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Condition	Intervention	Phase
Stroke	Behavioral: Word Retrieval Treatments for Aphasia	Phase I

Study Type:	Interventional
Study Design:	Treatment, Randomized, Single Blind (Investigator), Uncontrolled, Parallel Assignment, Efficacy Study
Official Title:	Communication Outcomes for Naming Treatments in Aphasia

Resource links provided by NLM:

MedlinePlus related topics: Aphasia Speech and Communication Disorders

U.S. FDA Resources

Further study details as provided by National Institute on Deafness and Other Communication Disorders (NIDCD):

Primary Outcome Measures:

Daily Probe Picture Naming [ Time Frame: daily probes from pretreatment to one month posttreatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Western Aphasia Battery [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
Boston Naming Test [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
Discourse Sample [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
Communicative Effectiveness Index [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]
Functional Outcomes Questionnaire for Aphasia [ Time Frame: pre- and post-treatment ] [ Designated as safety issue: No ]

Estimated Enrollment:	16
Study Start Date:	August 2008
Estimated Study Completion Date:	July 2011
Estimated Primary Completion Date:	May 2011 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Errorless Naming Treatment: Experimental	Behavioral: Word Retrieval Treatments for Aphasia Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.
Verbal+Gestural Facilitation: Experimental	Behavioral: Word Retrieval Treatments for Aphasia Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

Eligibility

Ages Eligible for Study:	21 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

left hemisphere stroke >4 months earlier aphasia with word retrieval impairments >21 years of age right handed speaker of English as the preferred language >6 grade education -

Exclusion Criteria:

history of developmental learning difficulties history of prior neurological illnesses chronic medical illnesses that restrict participation in speech therapy alcohol or drug dependence severe uncorrected impairments of vision or hearing

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Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00764400

Contacts

Contact: Anastasia M Raymer, PhD	757-683-4522	sraymer@odu.edu
Contact: Sheryl Spence	757-683-4117

Locations

United States, Virginia
Old Dominion University Speech and Hearing Clinic	Recruiting
Norfolk, Virginia, United States, 23529
Contact: Anastasia M Raymer, PhD 757-683-4522 sraymer@odu.edu
Principal Investigator: Anastasia Raymer, PhD

Sponsors and Collaborators

National Institute on Deafness and Other Communication Disorders (NIDCD)

Investigators

Principal Investigator:

Anastasia M Raymer, PhD

Old Dominion University

More Information

No publications provided

Responsible Party:	Old Dominion University ( Anastasia Raymer, Ph.D., Principal Investigator )
Study ID Numbers:	R15 DC009690, R15 DC009690
Study First Received:	September 30, 2008
Last Updated:	May 18, 2009
ClinicalTrials.gov Identifier:	NCT00764400 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by National Institute on Deafness and Other Communication Disorders (NIDCD):

aphasia, anomia, speech therapy, rehabilitation

Additional relevant MeSH terms:

Signs and Symptoms
Speech Disorders
Aphasia
Nervous System Diseases

Neurologic Manifestations
Language Disorders
Neurobehavioral Manifestations
Communication Disorders

ClinicalTrials.gov processed this record on February 08, 2010