Randomized Controlled Trial Comparing Efficacy and Tolerance of Four Pediculicides

Inclusion Criteria:

• Subject-male or female, child > 3 years and adult
• Pediculosis of scalp, confirmed by the identification of minimum 5 live lice with a fine-tooth comb
• Negative urine pregnancy test before inclusion for women of childbearing potential
• Use of a contraceptive method by hormonal contraceptives or IUDs or tubal ligation or condoms for women of childbearing potential
• Subject agreeing to participate in the study with written informed consent for participation
• Written consent of both parents for the minor patients.

Exclusion Criteria:

• Children under 3 years.
• Woman pregnant or lactating or without contraception
• Use of a pediculicide or lenticide treatment within 2 weeks before entry into the study
• Subject with known hypersensitivity to any component of the tested products
• Subject who participated in a clinical study in the 3 months prior to inclusion
• Ongoing treatment potentially interacting with the treatment under study (other pediculicide products)
• Subject undertreatment susceptible to influence the evaluation of the trial (including trimethoprim-sulfamethoxazole).
• Severe medical or psychiatric illness considered by the investigator as potentially dangerous to the subject or incompatible with the conduct of the study
• Asthma
• Subject unable for linguistic or psychiatric reasons to understand the information and give informed consent
• Subject refusing to give written consent
• Subject deprived of his liberty by administrative or judicial decision, or guardianship
• Patient hospitalized in a medical or social facility for another reason that biomedical research