Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2008 by Assaf-Harofeh Medical Center.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
Assaf-Harofeh Medical Center
ClinicalTrials.gov Identifier:
NCT00757796
First received: September 21, 2008
Last updated: NA
Last verified: September 2008
History: No changes posted
  Purpose

Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not demonstrated. Our hypothesis is that patients suffering from a more severe sleep apnea will demonstrate a greater degree of cognitive dysfunction.


Condition
Obstructive Sleep Apnea

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances

Resource links provided by NLM:


Further study details as provided by Assaf-Harofeh Medical Center:

Estimated Enrollment: 80
Study Start Date: October 2008
Detailed Description:

Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of sleep disturbances and the degree of cognitive dysfunction was not demonstrated.We intend to study 80 patients with various degrees of obstructive sleep apnea. All patients will undergo executive cognitive tests as well as tests to assess for levels of depression, anxiety and attention.

  Eligibility

Ages Eligible for Study:   20 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients aged 20 - 70 years with obstructive sleep apnea.

Criteria

Inclusion Criteria:

  1. Apnea hypopnea index>5
  2. Age 20 - 70 years

Exclusion Criteria:

  1. Pregnant women
  2. Known chronic cardiovascular or pulmonary disease
  3. Patients s/p CVA or brain damage
  4. Known depression or other psychiatric disorder
  5. Patients with severe cognitive dysfunction (MMSE<25)
  6. Patients receiving stimulants, antipsychotic or anti-depression medications
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Itzhak Shpirer, The Sleep Laboratory, Assaf Harofeh Medical Center, Zerifin, Israel
ClinicalTrials.gov Identifier: NCT00757796     History of Changes
Other Study ID Numbers: 143/06
Study First Received: September 21, 2008
Last Updated: September 21, 2008
Health Authority: Israel: Ethics Commission

Additional relevant MeSH terms:
Apnea
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Dyssomnias
Nervous System Diseases
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms
Signs and Symptoms, Respiratory
Sleep Disorders
Sleep Disorders, Intrinsic

ClinicalTrials.gov processed this record on November 24, 2014