Diagnosis of Exercise-Induced Bronchospasm (EIB) and Asthma in National Collegiate Athletic Association (NCAA) Division I Athletes
The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2008 by University of Arizona.
Recruitment status was Recruiting
Recruitment status was Recruiting
Sponsor:
University of Arizona
Collaborator:
GlaxoSmithKline
Information provided by:
University of Arizona
ClinicalTrials.gov Identifier:
NCT00752167
First received: September 11, 2008
Last updated: September 12, 2008
Last verified: September 2008
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Purpose
We hypothesize that exercise-induced bronchospasm (EIB) at the NCAA Division I collegiate level is over diagnosed, while poorly controlled asthma resulting in exercise-related symptoms in this same population may be under diagnosed, being erroneously attributed to EIB. This project will test individuals self-identified as having exercise induced bronchospasm or asthma, as well as gender-matched controls from the same sport, with eucapnic voluntary hyperventilation to assess for the presence of EIB or asthma. By making the correct diagnosis, improved health outcomes may be achieved and athletic performance may be enhanced.
| Condition |
|---|
|
Exercise Induced Bronchospasm, Asthma |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Cross-Sectional |
| Official Title: | Diagnosis of EIB and Asthma in NCAA Division I Athletes |
Resource links provided by NLM:
Further study details as provided by University of Arizona:
Primary Outcome Measures:
- Change in FEV1 following eucapnic voluntary hyperventilation [ Time Frame: 3-21 minutes ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Protection from fall in FEV1 following eucapnic voluntary hyperventilation by preadministration of albuterol [ Time Frame: 3-21 minutes ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 75 |
| Study Start Date: | February 2007 |
| Groups/Cohorts |
|---|
|
Case
all Division I athletes, male and female, at the University of Arizona that are currently being treated for either EIB or asthma by review of preparticipation physical forms or identified by the medical staff
|
|
Control
control athletes (ie, not currently being treated for either EIB or asthma by review of preparticipation physical forms or identified by the medical staff and/or not currently using asthma medications) from the same sport
|
Show Detailed Description Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Study Population
NCAA Varsity Division I athletes attending the University of Arizona
Criteria
Inclusion Criteria:
- varsity athlete
- ability and willingness to give written informed consent
Exclusion Criteria:
- inability to give written informed consent
- unwillingness to perform spirometry or eucapnic voluntary hyperventilation
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00752167
Contacts
| Contact: David Millward, MD | 520-626-6363 | millward@msu.edu |
| Contact: Mark A Brown, MD | 520-626-7780 | mabrown@arc.arizona.edu |
Locations
| United States, Arizona | |
| University of Arizona | Recruiting |
| Tucson, Arizona, United States, 85724 | |
| Contact: David Millward, MD 520-626-6363 millward@msu.edu | |
| Sub-Investigator: Mark A Brown, MD | |
| Principal Investigator: David Millward, MD | |
| Sub-Investigator: Stephen Paul, MD | |
| Sub-Investigator: Donald Porter, MD | |
| Sub-Investigator: Michael Stilson, MD | |
Sponsors and Collaborators
University of Arizona
GlaxoSmithKline
More Information
No publications provided
| Responsible Party: | David Millward, MD, University of Arizona |
| ClinicalTrials.gov Identifier: | NCT00752167 History of Changes |
| Other Study ID Numbers: | GSK 110189 |
| Study First Received: | September 11, 2008 |
| Last Updated: | September 12, 2008 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by University of Arizona:
|
exercise induced bronchospasm asthma athlete |
sports eucapnic voluntary hyperventilation albuterol |
Additional relevant MeSH terms:
|
Asthma Bronchial Spasm Asthma, Exercise-Induced Bronchial Diseases Respiratory Tract Diseases Lung Diseases, Obstructive |
Lung Diseases Respiratory Hypersensitivity Hypersensitivity, Immediate Hypersensitivity Immune System Diseases |
ClinicalTrials.gov processed this record on May 21, 2013