Urine Concentration of S100B in Extremely Premature Infants
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study. Is urine S100B concentration correlated with the serum concentration of S100B in infants born at 29-36 weeks gestation. The presence and severity of intracranial pathology on S100B concentration will be investigated. Further analysis will demonstrate if birth weight, daily fluid intake, urine output, and urine creatinine influence this relationship.
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Correlation of Urine Concentration of S100B in Extremely Premature Infants With Gestational Age and Severity of Intraventricular Hemorrhage|
|Study Start Date:||November 2002|
|Study Completion Date:||April 2005|
|Primary Completion Date:||February 2005 (Final data collection date for primary outcome measure)|