Evaluation of an Antithrombotic Therapeutic Strategy in Pregnant Women (STRATHEGE)
The venous thromboembolism is one of the first causes of maternal mortality. Until 2003, only a few recommendations were available on the optimal use of antithrombotic therapy as a preventive measure against thromboembolism in pregnant women. In this study, we propose :
- To gather the experts who took part in the French consensus conference and the local experts to create a score in accordance with the national and international consensus and to give some precise therapeutic strategies.
- To evaluate the discriminant, feasible and useful character of this new score by a random prospective multicentric study including 2280 pregnant women with a risk of thromboembolism or placental vascular pathology who will benefit from therapeutic strategies defined by the new score.
Placental Vascular Pathologies
Venous Thromboembolism Diseases
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Prospective Multicentric Evaluation of an Antithrombotic Therapeutic Strategy in Pregnant Women With a Risk of Thromboembolism and/or a Risk of Placental Vascular Complication, Strategy Determined With a Risk Score.|
- Occuring of symptomatic thromboembolic events, and/or placental vascular pathology, and/or any other pregnancy pathology requiring hospitalization and/or any complications from the antithrombotic treatment [ Time Frame: first, second or third trimester during pregnancy or post-partum ] [ Designated as safety issue: No ]
|Study Start Date:||June 2008|
|Study Completion Date:||June 2013|
|Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
Purpose : To create a score inspired by our first experience i.e. simple, standardized and quickly usable in day-to-day practice to individualize antithrombotics prescription to women at risk.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00745212
|Service de Gynécologie Obstétrique - CHU Saint-Etienne|
|Saint-Etienne, France, 42055|
|Principal Investigator:||Céline CHAULEUR, MD PhD||CHU de Saint-Etienne|