Use Of Capnography As Surrogate Measure Of PC02 In Medical Intensive Care Unit (ICU) Patients

This study has been terminated.
(Principal Investigator (central contact) has left the organization and requests the study be terminated)
Sponsor:
Information provided by:
Lahey Clinic
ClinicalTrials.gov Identifier:
NCT00744614
First received: August 29, 2008
Last updated: October 19, 2010
Last verified: October 2010
  Purpose

The purpose of this study is to evaluate the use of Capnography (Continuous recording of the carbon dioxide content of expired air)as an alternative test to measure PC02 levels in patients with asthma, chronic obstructive pulmonary (COPD,interstitial lung disease(ILD)or coronary disease who are at risk of intubation.


Condition Intervention
Asthma
Chronic Obstructive Pulmonary Disease
Interstitial Lung Disease
Procedure: Capnography

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Use Of Capnography As Surrogate Measure Of PC02 In Medical ICU Patients

Resource links provided by NLM:


Further study details as provided by Lahey Clinic:

Primary Outcome Measures:
  • PCO2 level [ Time Frame: 6 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Time to intubation [ Time Frame: 6 months ] [ Designated as safety issue: No ]

Estimated Enrollment: 70
Study Start Date: November 2007
Study Completion Date: October 2010
Primary Completion Date: October 2010 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1
Medical Intensive care unit patients with asthma, COPD, ILD or coronary disease who are at risk of intubation
Procedure: Capnography
A technique for monitoring the concentration or partial pressure of CO2 levels in respiratory gases

Detailed Description:

This is a prospective study to evaluate the usefulness of capnography as a non-invasive, accurate method of measuring of PC02 levels in medical intensive care unit patients with asthma, COPD, ILD, or coronary disease who are at risk of intubation.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

MICU patients who are at risk of intubation and who have a history of asthma, COPD, ILD or coronary disease.

Criteria

Inclusion Criteria:

  • Medical Intensive Care Patients
  • Not intubated
  • Age 18 or older
  • History of any one of the following: asthma, COPD, ILD, or coronary disease

Exclusion Criteria:

  • Sepsis
  • Life expectancy less than 1 month
  • Requiring BIPAP
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00744614

Locations
United States, Massachusetts
Lahey Clinic, Inc.
Burlington, Massachusetts, United States, 01805
Sponsors and Collaborators
Lahey Clinic
Investigators
Principal Investigator: David R. Riker, M.D. Lahey Clinic, Inc.
  More Information

Publications:
Responsible Party: David Riker, M.D., Lahey Clinic, Inc.
ClinicalTrials.gov Identifier: NCT00744614     History of Changes
Other Study ID Numbers: 2007-115
Study First Received: August 29, 2008
Last Updated: October 19, 2010
Health Authority: United States: Institutional Review Board

Keywords provided by Lahey Clinic:
PC02
Respiratory Rate
Arterial blood gas
Intubation
Capnography

Additional relevant MeSH terms:
Asthma
Lung Diseases
Respiration Disorders
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Interstitial
Lung Diseases, Obstructive
Bronchial Diseases
Respiratory Tract Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases

ClinicalTrials.gov processed this record on April 17, 2014