HPV Infections in Older Women
The purpose of this study is to determine risk factors for HPV infections in 25 to 65 year old women who report having used internet dating websites in the past year.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||HPV Infections in Older Women|
- High-risk HPV DNA [ Time Frame: Every 4 months for 1 year ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
Vaginal swab samples for HPV DNA testing
|Study Start Date:||July 2008|
|Study Completion Date:||May 2011|
|Primary Completion Date:||May 2011 (Final data collection date for primary outcome measure)|
Whether older women are susceptible to acquiring new, persistent high-risk (HR) HPV infections from new sex partners is largely unknown. This is a longitudinal study of predictors of HR HPV infections in two populations of women aged 25 to 44 and 45 to 65 who have used internet dating websites in the past year. 300 women will be recruited and mailed kits for self-collecting vaginal specimens for HPV DNA testing. Women will self-collect four sets of vaginal specimens four months apart, and complete sexual behavior questionnaires at the time of each self-collection. We will identify behavioral and health predictors of type-specific HR HPV infections, predictors of repeatedly-detected HR HPV infections, and evaluate study participants' experiences with self-collecting vaginal specimens and attitudes towards HPV vaccination and cervical cancer screening. This information is important for developing guidelines for HPV vaccine implementation and cervical cancer screening guidelines in populations of older women.
|United States, Washington|
|University of Washington|
|Seattle, Washington, United States, 98103|
|Principal Investigator:||Rachel L Winer, PhD||University of Washington|