Retinal Nerve Fiber Layer Thickness Measurement on Parapapillary Atrophy With the Cirrus High-Definition (HD) Optical Coherence Tomography (OCT)
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Purpose
Retinal nerve fiber layer (RNFL) thickness measurement on the parapapillary atrophy is incorrect. Because a new spectral domain OCT, the Cirrus HD OCT, uses a movable circle to analyze the RNFL thickness, we may suggest a new analysis strategy for the parapapillary atrophy.
| Condition |
|---|
|
Glaucoma |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Retrospective |
| Official Title: | Retinal Nerve Fiber Layer Thickness Measurement on Parapapillary Atrophy With |
- Retinal nerve fiber layer thickness [ Time Frame: when the OCT images are taking ] [ Designated as safety issue: No ]
- Size of parapapillary atrophy [ Time Frame: when the OCT images are taking ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 30 |
| Study Start Date: | September 2008 |
| Estimated Study Completion Date: | March 2009 |
| Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
1
No parapapillary atrophy
|
|
2
Parapapillary atrophy
|
Detailed Description:
Recently, the retinal nerve fiber layer (RNFL) thickness measurement using the optical coherence tomography (OCT) becomes very useful to detect such a glaucomatous damage. However, there are some difficult cases including parapapillary atrophy to perform this measurement. Because the RNFL thickness is so sensitive to the position of measurement and the measurement of RNFL thickness on parapapillary atrophy is incorrect, it is difficult to determine exact RNFL thickness in patients with a large parapapillary atrophy. In the present study, we want to find the proper method to analyze the RNFL thickness on parapapillary atrophy. The previous OCT used a fixed circle to measure the RNFL thickness, but the new spectral domain OCT, the Cirrus HD OCT, uses a movable one. Therefore, we may suggest a new analysis strategy for the parapapillary atrophy.
Eligibility| Ages Eligible for Study: | 18 Years to 70 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Non-Probability Sample |
Subjects with or without parapapillary atrophy
Inclusion Criteria:
- Qualified OCT images (signal strength > or = 8)
Exclusion Criteria:
- Previous intraocular surgery history
- Media opacity
- DM
Contacts and Locations| Contact: Gong Je Seong, MD, PhD | 82-2-2019-3441 | gjseong@yuhs.ac |
| Korea, Republic of | |
| Gong Je Seong | Not yet recruiting |
| Seoul, Korea, Republic of, 135-720 | |
| Contact: Gong Je Seong, MD, PhD 82-2-2019-3441 gjseong@yuhs.ac | |
| Principal Investigator: Gong Je Seong, MD, PhD | |
| Principal Investigator: | Gong Je Seong, MD, PhD | Yonsei University College of Medicine |
More Information
No publications provided
| Responsible Party: | Gong Je Seong, Yonsei University College of Medicine |
| ClinicalTrials.gov Identifier: | NCT00742196 History of Changes |
| Other Study ID Numbers: | 3-2008-0076-2 |
| Study First Received: | August 26, 2008 |
| Last Updated: | August 26, 2008 |
| Health Authority: | Korea: Food and Drug Administration |
Keywords provided by Yonsei University:
|
Parapapillary atrophy Retinal nerve fiber layer thickness Glaucoma Cirrus OCT |
Additional relevant MeSH terms:
|
Glaucoma Atrophy Ocular Hypertension Eye Diseases Pathological Conditions, Anatomical |
ClinicalTrials.gov processed this record on May 23, 2013