|
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
![]() |
||||||||||||||||||||||||||||||||||||
| Sponsor: | Lawson Health Research Institute |
|---|---|
| Collaborator: |
Canadian Association of Emergency Physicians |
| Information provided by: | Lawson Health Research Institute |
| ClinicalTrials.gov Identifier: | NCT00736554 |
Purpose
Staphylococcus aureus is the most common bacteria responsible for skin, bone, and muscle infections. Recent studies from the United States have suggested that a type of this bacterium called methicillin resistant S. aureus (MRSA) has become dramatically more common, especially the community strain. However, Canadian data is still largely lacking. This study aims to determine the prevalence of community acquired (CA) MRSA among patients presenting with skin and soft tissue infections to the Urgent Care Center and Emergency Departments in London, Ontario. This will be determined by taking swabs at enrollment from patient's noses, throats, and sites of infection. Patients will be asked to complete a health questionnaire with the goal of identifying risk factors associated with CA-MRSA. Through follow-up swabs of participants' noses and throats at one and three months, the effects of treatment on patient's carrying MRSA will be determined. Results may be used to form guidelines for empirical S aureus treatment in the region, reducing possible morbidity and mortality from delayed or suboptimal treatment of CA-MRSA infections. Improved understanding of risk factors associated with MRSA infection in a Canadian setting, may also change the practice of physicians considering empiric antibiotic therapy for skin and soft tissue infections.
| Condition |
|---|
|
Bacterial Infections Gram-Positive Bacterial Infections Staphylococcal Infections |
| Study Type: | Observational |
| Study Design: | Cohort, Prospective |
| Official Title: | Prevalence of MRSA in Skin and Soft Tissue Infections in Two Ontario Emergency Departments. |
| Estimated Enrollment: | 152 |
| Study Start Date: | July 2008 |
| Estimated Study Completion Date: | March 2009 |
| Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
Show Detailed Description
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Selection of Participants: The objective of this prospective study is to determine the prevalence of MRSA and community acquired MRSA (CA-MRSA) in adult patients (>17 yrs old) presenting with skin or soft tissue infections to the emergency departments (EDs) of an academic health care setting in London, Ontario.
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Shelley L McLeod, MSc, BSC (Hons) | 519-685-8500 ext 76089 | shelley.mcleod@lhsc.on.ca |
| Canada, Ontario | |
| London Health Sciences Centre | Recruiting |
| London, Ontario, Canada, N6A 5W9 | |
| Contact: Shelley L McLeod, MSc, BSc (Hons) 519-685-8500 ext 76089 shelley.mcleod@lhsc.on.ca | |
| Principal Investigator: Christopher MB Fernandes, FRCP, FACEP, MD | |
| Sub-Investigator: Karl Theakston, MD, MSc | |
| Sub-Investigator: Michael A John, MSc, MB,ChB, FRCPC | |
| Sub-Investigator: Zafar Hussain, MD, FRCPC | |
| Sub-Investigator: Marina Salvadori, MD, FRCPC | |
| Sub-Investigator: Cimi Achiam, MD, BSc Hons | |
| Sub-Investigator: Jamie Seabrook, MA, BA | |
| Sub-Investigator: Shelley L McLeod, MSc, BSc (Hons) | |
| Principal Investigator: | Christopher MB Fernandes, FRCP, FACEP, MD | University of Western Ontario, Canada |
More Information
| Responsible Party: | London Health Sciences Centre ( Dr. Christopher Fernandes ) |
| Study ID Numbers: | R-08-173, 13871E |
| Study First Received: | August 14, 2008 |
| Last Updated: | August 15, 2008 |
| ClinicalTrials.gov Identifier: | NCT00736554 History of Changes |
| Health Authority: | Canada: Ethics Review Committee |
|
Staphylococcus aureus CA-MRSA skin and soft tissue infections resistance emergency department |
|
Bacterial Infections Staphylococcal Infections Communicable Diseases Disease Attributes Gram-Positive Bacterial Infections |
Pathologic Processes Soft Tissue Infections Emergencies Infection |