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Interval Training in Young Healthy Individuals

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:
NCT00733941
First received: August 12, 2008
Last updated: January 5, 2012
Last verified: January 2012
History of Changes
  Purpose

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training


Condition Intervention
Healthy Subjects
Exercise Test
 Behavioral: High frequency training
Behavioral: normal frequence training

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Interval Training: Training, Detraining and Retraining; an Interventional Study

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Oxygen uptake [ Time Frame: Before and after the training-, detraining- and retraining-phase ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Cardiac function and skeletal muscle enzyme activity [ Time Frame: After training, detraining and retraining ] [ Designated as safety issue: No ]

Enrollment: 24
Study Start Date: September 2008
Study Completion Date: December 2009
Primary Completion Date: June 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: High frequency training
24 interval exercises performed 8 times per week
 Behavioral: High frequency training
24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining
Experimental: Normal frequency training
24 interval exercises performed 3 times per week
 Behavioral: normal frequence training
24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Detailed Description:

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

  Eligibility

Ages Eligible for Study:   18 Years to 27 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria:

  • Hypertension, diabetes and cardiovascular disease.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00733941

Locations
Norway
Norwegian University of Science and Technology
Trondheim, Norway, 7020
NTNU
Trondheim, Norway, 7489
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
Principal Investigator: Øivind Rognmo, PhD Norwegian University of Science and Technology
Principal Investigator: Ulrik Wisløff, Professor NTNU
  More Information

No publications provided

Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00733941     History of Changes
Other Study ID Numbers: 4.2008.1755
Study First Received: August 12, 2008
Last Updated: January 5, 2012
Health Authority: Norway: Norwegian Social Science Data Services
Norway:National Committee for Medical and Health Research Ethics

Keywords provided by Norwegian University of Science and Technology:
Exercise test
Running
Arterial diameter
Monitoring, physiologic
Oxygen Consumption

ClinicalTrials.gov processed this record on May 19, 2013