Surgical Treatment of Hilar Cholangiocarcinoma: Minor or Major Liver Resection?
The investigators conducted a prospective study to determine the safety and efficacy of minor and major hepatectomy selected by predetermined criteria in 138 patients with hilar cholangiocarcinoma. In selected patients, minor liver resection was a good treatment.
Procedure: Minor or Major Liver Resection
|Official Title:||Surgical Treatment of Hilar Cholangiocarcinoma: Minor or Major Liver Resection?|
- On multivariate analysis, prognostic factors significantly impacted on long-term survival were UICC tumor stage and histopathologic grade.
|No Intervention: Control group||Procedure: Minor or Major Liver Resection|
Objective: To determine the safety and efficacy of minor and major hepatectomy selected by predetermined criteria in patients with hilar cholangiocarcinoma (HC).
Summary Background Data: For HC treated with hepatectomy, the extent of liver resection remains controversial despite extensive studies.
Methods: From January 2000 to December 2007, we prospectively studied patients who received surgical treatment for HC. Of the 187 patients who were surgically treated, 138 (73.8%) underwent resection with a curative intent. Minor hepatectomy was carried out in 93 patients who had Bismuth-Corlette types I, II and III HC without hepatic artery/portal vein invasion; and major hepatectomy in 45 patients who had type III HC with hepatic artery/portal vein invasion, or type IV HC.