Procalcitonin Level and Kinetics in Children With Bacterial Infections

This study has been completed.
Sponsor:
Information provided by:
Shaare Zedek Medical Center
ClinicalTrials.gov Identifier:
NCT00714402
First received: July 9, 2008
Last updated: May 17, 2011
Last verified: January 2009
  Purpose

The purposes of this study are:

  1. To determine whether procalcitonin level at admission of pediatric patients with bacterial infections can be used as a marker for prediction of defervescence and hospitalization length
  2. To examine the kinetics of procalcitonin in pediatric patients with bacterial infections and persistent fever

Condition
Bacterial Infections
Bacteremia
Meningitis
Urinary Tract Infection
Mastoiditis
Lobar Pneumonia
Septic Arthritis
Cellulitis
Osteomyelitis

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Procalcitonin Level as a Prognostic Marker and Its' Kinetics in Children With Bacterial Infections

Resource links provided by NLM:


Further study details as provided by Shaare Zedek Medical Center:

Primary Outcome Measures:
  • time to defervescence [ Time Frame: discharge ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • length of hospitalization [ Time Frame: discharge ] [ Designated as safety issue: No ]

Biospecimen Retention:   None Retained

whole blood


Estimated Enrollment: 50
Study Start Date: August 2008
Groups/Cohorts
a
children with proven of probable invasive bacterial infections

  Eligibility

Ages Eligible for Study:   up to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

hospitalized patients at date of admission

Criteria

Inclusion Criteria:

  • Positive blood, urine, synovial, bone, pleural effusion, abscess or CSF culture
  • Cellulitis, lobar pneumonia, osteomyelitis,
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00714402

Locations
Israel
Shaare Zedek Medical Center
Jerusalem, Pob 3235, Israel, 91031
Sponsors and Collaborators
Shaare Zedek Medical Center
Investigators
Principal Investigator: Yechiel Schlesinger, MD Shaare Zedek Medical Center
  More Information

Publications:

Responsible Party: Yechiel Schlesinger, Shaare Zedek Medical Center
ClinicalTrials.gov Identifier: NCT00714402     History of Changes
Other Study ID Numbers: pct.ctil
Study First Received: July 9, 2008
Last Updated: May 17, 2011
Health Authority: Israel: Helsinki committee

Keywords provided by Shaare Zedek Medical Center:
UTI

Additional relevant MeSH terms:
Arthritis
Arthritis, Infectious
Bacteremia
Bacterial Infections
Cellulitis
Mastoiditis
Meningitis
Osteomyelitis
Pneumonia
Urinary Tract Infections
Joint Diseases
Musculoskeletal Diseases
Infection
Sepsis
Systemic Inflammatory Response Syndrome
Inflammation
Pathologic Processes
Skin Diseases, Infectious
Suppuration
Connective Tissue Diseases
Bone Diseases, Infectious
Bone Diseases
Otitis Media
Otitis
Ear Diseases
Otorhinolaryngologic Diseases
Central Nervous System Infections
Central Nervous System Diseases
Nervous System Diseases
Lung Diseases

ClinicalTrials.gov processed this record on August 28, 2014