Speech and Language Therapy After Stroke - Full Text View

Speech and Language Therapy After Stroke

This study is currently recruiting participants.
Verified by National Institute on Deafness and Other Communication Disorders (NIDCD), July 2008

Sponsors and Collaborators:	National Institute on Deafness and Other Communication Disorders (NIDCD) Rehabilitation Institute of Chicago
Information provided by:	National Institute on Deafness and Other Communication Disorders (NIDCD)
ClinicalTrials.gov Identifier:	NCT00713050

Purpose

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Condition	Intervention
Ischemic Stroke	Behavioral: Imitate Therapy

MedlinePlus related topics:

Aphasia

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double Blind (Subject, Outcomes Assessor), Single Group Assignment

Official Title:	Neurophysiological Measurement in Aphasia Treatment

Further study details as provided by National Institute on Deafness and Other Communication Disorders (NIDCD):

Primary Outcome Measures:

changes in scores on Western Aphasia Battery [ Time Frame: Four months ] [ Designated as safety issue: No ]

Estimated Enrollment:	57
Study Start Date:	August 2007
Estimated Primary Completion Date:	August 2013 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: Experimental Experimental arm	Behavioral: Imitate Therapy Imitation-based computer therapy
Control: Active Comparator Control Arm	Behavioral: Imitate Therapy Imitation-based computer therapy

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI)
Aphasia
Visual attention and language comprehension sufficient to perform imitation fMRI tasks
Right handed (prior to stroke)

Exclusion Criteria:

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00713050

Contacts


Contact: Robert Fowler	773-834-7780	rfowler@uchicago.edu

Locations


United States, Illinois
	University of Chicago	Recruiting
	Chicago, Illinois, United States, 60637
	Contact: Robert Fowler 773-834-7780 rfowler@uchicago.edu
	Principal Investigator: Steven Small, M.D., Ph.D.
	Rehabilitation Institute of Chicago	Recruiting
	Chicago, Illinois, United States, 60611

Sponsors and Collaborators

National Institute on Deafness and Other Communication Disorders (NIDCD)

Rehabilitation Institute of Chicago

Investigators


Principal Investigator:	Steven Small, M.D.,Ph.D.	University of Chicago

More Information

Responsible Party:	University of Chicago ( Dr. Steven Small, M.D., Ph.D./Professor )
Study ID Numbers:	5R01DC7488-3
First Received:	July 9, 2008
Last Updated:	July 9, 2008
ClinicalTrials.gov Identifier:	NCT00713050
Health Authority:	United States: Food and Drug Administration; United States: Federal Government

Keywords provided by National Institute on Deafness and Other Communication Disorders (NIDCD):

stroke

aphasia

imitation

mirror neuron

Study placed in the following topic categories:

Cerebral Infarction

Aphasia

Stroke

Vascular Diseases

Central Nervous System Diseases

Ischemia

Brain Diseases

Cerebrovascular Disorders

Additional relevant MeSH terms:

Nervous System Diseases

Cardiovascular Diseases

ClinicalTrials.gov processed this record on September 05, 2008