Training-induced Cerebral Reorganization in Schizophrenia
The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
|Official Title:||Training-induced Cerebral Reorganization in Schizophrenia|
- Event related potential MEG, test scores in word fluency and verbal learning tasks [ Time Frame: pre and post intervention ] [ Designated as safety issue: No ]
- Symptom severity, GAF score [ Time Frame: pre and post intervention ] [ Designated as safety issue: No ]
|Study Start Date:||January 2008|
|Study Completion Date:||January 2010|
|Primary Completion Date:||June 2009 (Final data collection date for primary outcome measure)|
20 schizophrenic patients
Behavioral: Brain Fitness Program
Computer-aided cognitive program designed for intensive training of auditory perception, memory and attention
Active Comparator: CP
19 schizophrenic patients
Computer-aided cognitive program for cognitive abilities
No Intervention: HCG
20 healthy age and sex matched subjects
Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease.
In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing.
The other training involves a variability of cognitive abilities.
Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.
|University of Konstanz|
|Konstanz, Baden Württenberg, Germany, 78457|
|Study Chair:||Brigitte Rockstroh, Prof. Dr.||University of Konstanz, Department of Psychology|