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| Sponsored by: |
University Hospital Inselspital, Berne |
| Information provided by: | University Hospital Inselspital, Berne |
| ClinicalTrials.gov Identifier: | NCT00695487 |
Purpose
The investigators evaluate if intravenously applied THC (Cannabis) reduces postoperative Nausea and vomiting. THC will be given during anesthesia before emergence. We measure how long and how effective it reduces PONV
| Condition | Intervention |
|
Nausea Vomiting |
Drug: THC 9-d-tetra hydro cannabinol |
| MedlinePlus related topics: | Anesthesia Nausea and Vomiting |
| ChemIDplus related topics: | Cannabis Cannabinol GW-1000 |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Double Blind (Subject, Investigator), Placebo Control, Parallel Assignment, Efficacy Study |
| Official Title: | Does Intravenous Cannabis Reduce Postoperative Nausea and Vomiting (PONV)? |
| Estimated Enrollment: | 320 |
| Study Start Date: | July 2008 |
| Estimated Study Completion Date: | June 2010 |
| Estimated Primary Completion Date: | January 2010 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|
1: Experimental
Receives 0.125mg/kg THC before emergence
|
Drug: THC 9-d-tetra hydro cannabinol
0.125mg/kg iv one time
|
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2: Placebo Comparator
Receives NaCl before emergence
|
Drug: THC 9-d-tetra hydro cannabinol
0.125mg/kg iv one time
|
Eligibility
| Ages Eligible for Study: | 18 Years to 70 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Robert Greif, MD | 0041 31 6321629 | robert.greif@insel.ch |
| Contact: Lorenz G Theiler, MD | 0041 31 6321629 | lorenz.theiler@insel.ch |
| Switzerland | |||||
| Inselspital, Bern University Hospital | Recruiting | ||||
| Bern, Switzerland, 3010 | |||||
| Contact: Robert Greif, MD 0041316322111 robert.greif@insel.ch | |||||
| Contact: Lorenz G Theiler, MD 0041316322111 loren.theiler@insel.ch | |||||
| University Hospital Inselspital, Berne |
| Study Director: | Robert Greif, MD | Department of Anesthesia, Bern University Hospital , Switzerland |
More Information
| Responsible Party: | Department of Anesthesia, Inselspital, Bern University Hospital, Switzerland ( Robert Greif, M.D. Associate Professor ) |
| Study ID Numbers: | KEK240_07, THC-001 |
| First Received: | June 10, 2008 |
| Last Updated: | August 22, 2008 |
| ClinicalTrials.gov Identifier: | NCT00695487 |
| Health Authority: | Switzerland: Federal Office of Public Health |
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