Vitamin D and Type 2 Diabetes - a Cross Sectional Study
The purpose of the study is to describe vitamin D status among patients with type 2 diabetes and to determine the association between serum 25-hydroxyvitamin D and glycemic control, markers of inflammation and blood pressure
Type 2 Diabetes Mellitus
|Study Design:||Observational Model: Cohort
Time Perspective: Cross-Sectional
|Official Title:||Vitamin D and Type 2 Diabetes - a Cross Sectional Study|
- Vitamin D status and its association with inflammation, glycemic control, lipids and blood pressure. [ Time Frame: December 08 ] [ Designated as safety issue: No ]
- Lifestyle (exercise, sun exposure, food intake) [ Time Frame: December 08 ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
Blood samples, urine.
|Study Start Date:||June 2008|
|Study Completion Date:||April 2009|
|Primary Completion Date:||April 2009 (Final data collection date for primary outcome measure)|
The cohort consists of type 2 diabetics from the outpatient clinic at Silkeborg Hospital.
It has been estimated that 1 billion people worldwide have vitamin D deficiency or insufficiency. It is well known that vitamin D deficiency causes osteoporosis, increases the risk of fracture and causes muscle weakness. But there is now evidence that calcium malnutrition and hypovitaminosis D are predisposing conditions for various common chronic diseases such as malignancies (particularly colon, breast and prostate) chronic inflammatory and autoimmune disease (inflammatory bowel disease, multiple sclerosis) as well as metabolic disorders (metabolic syndrome, hypertension).
It has also been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus.
The purpose of this study is to determine vitamin D status among type 2 diabetics in our outpatient clinic and examine the relationship between vitamin D status , calcium and phosphorous metabolism, inflammatory markers, glycemic control, blood pressure and lipid profile.
Moreover the patients are asked to answer a questionnaire regarding lifestyle, exercise, sun exposure and food intake.
|Principal Investigator:||Lotte Oeskov, MD||Medical Department, Silkeborg Hospital, Falkevej 1-3, 8600 Silkeborg, Denmark|