Graduated Embryo Score (GES) in the Fresh Cycle Predicts Outcome From Frozen Embryo Transfer (GES/FET)

This study has been completed.
Sponsor:
Information provided by:
Sher Institute for Reproductive Medicine, Las Vegas
ClinicalTrials.gov Identifier:
NCT00694434
First received: June 6, 2008
Last updated: June 9, 2008
Last verified: June 2008
  Purpose

Evaluation of embryo quality in the fresh cycle as a predictor of outcome from frozen embryo transfer.


Condition
Infertility

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Graduated Embryo Score (GES) Int he Fresh Cycle Predicts Outcome From Frozen Embryo Transfer

Resource links provided by NLM:


Further study details as provided by Sher Institute for Reproductive Medicine, Las Vegas:

Primary Outcome Measures:
  • On-going gestation (beyond 8 wks) [ Time Frame: Fetal heart activity at 8 weeks of gestation ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Implantation rate (gestational sacs/ embryos transferred) [ Time Frame: 8 weeks of gestation ] [ Designated as safety issue: No ]

Enrollment: 183
Study Start Date: January 2002
Study Completion Date: December 2007
Primary Completion Date: December 2007 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Patients with 2 or more frozen blastocyst that scored GES 70 or better in the fresh cycle.
2
Patients with 2 or more frozen blastocysts scoring GES <70 in the fresh cycle.

Detailed Description:

Outcomes from frozen embryo transfer reviewed based on the quality of the embryos in the ftresh cycle as assessed by the Graduatede embryo score.

  Eligibility

Ages Eligible for Study:   21 Years to 44 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

All IVF patients at our center between 2002 and 2007 with at least 2 frozen blastocysts undergoing frozen embryo transfer.

Criteria

Inclusion Criteria:

  • 2 frozen blastocysts
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00694434

Locations
United States, Nevada
Sher Institute for Reproductive Medicine
Las Vegas, Nevada, United States, 89118
Sponsors and Collaborators
Sher Institute for Reproductive Medicine, Las Vegas
Investigators
Principal Investigator: Jeffrey D Fisch, M.D. Sher Institute
  More Information

No publications provided

Responsible Party: Jeffrey Fisch, M.D., Sher Institute
ClinicalTrials.gov Identifier: NCT00694434     History of Changes
Other Study ID Numbers: 1-Fisch
Study First Received: June 6, 2008
Last Updated: June 9, 2008
Health Authority: United States: Institutional Review Board

Keywords provided by Sher Institute for Reproductive Medicine, Las Vegas:
Cryopreservation
Frozen embryo transfer
Graduated Embryo Score

Additional relevant MeSH terms:
Infertility
Genital Diseases, Female
Genital Diseases, Male

ClinicalTrials.gov processed this record on October 23, 2014