Using the Digital EEG Spectral Analysis in Assessing Neuroelectrical Processing Abnormalities in Autism - Full Text View

Purpose

Our objective is to use neuroelectrical measures to determine the degree of processing abnormalities in individuals with Autism. The study will survey processing patterns and will locate and evaluate the degree(s) of abnormalities for further study. The abnormal results of comprehensive neuroelectrical evaluations of individuals with Autism when compared to the normative database will provide objective, verifiable, neurophysiological information with which to form novel approaches to the disorder.

Condition

Autistic Disorder
Autism, Early Infantile
Autism, Infantile

MedlinePlus related topics:

Autism

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Other

Official Title:	Using the Digital EEG Spectral Analysis in Assessing Neuroelectrical Processing Abnormalities in Autism

Further study details as provided by Yellen & Associates, Inc.:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	200
Study Start Date:	June 2008
Estimated Study Completion Date:	December 2011
Estimated Primary Completion Date:	January 2009 (Final data collection date for primary outcome measure)

Detailed Description:

The research method will be: gathering, analyzing and utilizing data.

We will observe research subjects through neuroelectrical instrumentation, then, compare results to retrospective information collected from research subjects and a normative database.

A qualified neurologist thoroughly familiar with electrophysiology will interpret the data, and analyze it to explore the abnormalities.

The hypothesis will be evaluated.

We will, then, utilize the results to find data-based forms of treatment for those with the disorder.

Eligibility

Ages Eligible for Study:	5 Years to 25 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

The study population includes individuals with Autism without exclusion on the basis of sex, gender, race or ethnicity. There will be 100 research subjects, with a ratio of four males to one female, and those being approximately sixty-five children and thirty-five adults.

Criteria

Inclusion Criteria:

The study will include children between the ages of five and eighteen, adults from the age of nineteen to twenty-five, and those with the diagnosis of Autism and Autism Spectrum Disorders.

Exclusion Criteria:

those with mental retardation
those with any other neurological disorder
those that cannot sit in a chair for ninety minutes
those that have been previously diagnosed with a seizure disorder
those who are blind and/or deaf
those who are not ambulatory
those who cannot understand English
those that are not a resident of Los Angeles County

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00693953

Locations


United States, California
	Yellen & Associates, Inc.	Not yet recruiting
	Northridge, California, United States, 91326
	Contact: Dr. Andrew Yellen, PhD 818-360-3078 ext 103 docyellen@yellenandassociates.com
	Contact: Dr. Andrew Yellen, PhD 818-360-3078 ext 103 docyellen@yellenandassociates.com
	Principal Investigator: Andrew G Yellen, Phd
	Sub-Investigator: Thomas Schweller, MD
	Sub-Investigator: Tom Ward

Sponsors and Collaborators

Yellen & Associates, Inc.

Investigators


Principal Investigator:	Andrew G Yellen, PhD	President, Yellen & Associates, Inc.

Study Chair:	Thomas Schweller, MD	Neurologist

More Information

Responsible Party:	Yellen & Associates, Inc. ( Dr. Andrew G. Yellen )
Study ID Numbers:	PA-06-278
First Received:	June 5, 2008
Last Updated:	June 17, 2008
ClinicalTrials.gov Identifier:	NCT00693953
Health Authority:	United States: Institutional Review Board

Keywords provided by Yellen & Associates, Inc.:

Evoked Potentials

Evoked Potentials, Auditory

Evoked Potentials, Visual

Electroencephalography

Brain Mapping

Study placed in the following topic categories:

Child Development Disorders, Pervasive

Developmental Disabilities

Mental Disorders

Autistic Disorder

Mental Disorders Diagnosed in Childhood

Congenital Abnormalities

ClinicalTrials.gov processed this record on September 05, 2008

Sponsored by:	Yellen & Associates, Inc.
Information provided by:	Yellen & Associates, Inc.
ClinicalTrials.gov Identifier:	NCT00693953