Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD) - Tabular View

Tracking Information

First Received Date ^ICMJE

May 22, 2008

Last Updated Date

June 22, 2009

Start Date ^ICMJE

February 2008

Primary Completion Date

February 2008 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Fractional anisotropy coefficient if fronto-cerebello-frontal loops. [ Time Frame: visite 1 ] [ Designated as safety issue: No ]

Original Primary Outcome Measures ^ICMJE

Same as current

Change History

Complete list of historical versions of study NCT00684931 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)

Official Title ^ICMJE

Alterations of Fronto-Cerebello-Frontal Loops in Attention Deficit Hyperactivity Disorder (ADHD) : A Study Using Magnetic Resonance Imaging (MRI)

Brief Summary

The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.

Detailed Description

ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.

Study Phase

Study Type ^ICMJE

Interventional

Study Design ^ICMJE

Basic Science, Non-Randomized, Open Label, Parallel Assignment

Condition ^ICMJE

Attention Deficit Disorder With Hyperactivity

Intervention ^ICMJE

Other: Imaging

Study Arms / Comparison Groups

Experimental: patients with Attention Deficit Disorder with or without Hyperactivity
Sham Comparator: healthy volunteer without Attention Deficit Hyperactivity Disorder

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Terminated

Enrollment ^ICMJE

Completion Date

July 2008

Primary Completion Date

February 2008 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Patient with ADHD :

Diagnosis of ADHD
18 - 35 years old

Healthy volunteer :

18 - 35 years old
no ADHD diagnosed

Exclusion Criteria:

Associated neurological or psychiatric pathologies
Pregnant woman
MRI counter indication

Gender

Both

Ages

18 Years to 35 Years

Accepts Healthy Volunteers

Yes

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

France

Administrative Information

NCT ID ^ICMJE

NCT00684931

Responsible Party

Jean-Pierre LEROY / Clinical Research and Innovation Director, University Hospital, Bordeaux

Study ID Numbers ^ICMJE

CHUBX 2007/21

Study Sponsor ^ICMJE

University Hospital, Bordeaux

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:

Manuel BOUVARD, MD

Charles Perrens Hospital

Information Provided By

University Hospital, Bordeaux

Verification Date

June 2009

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP