Anesthesia for Dental Treatment in Cardiac Patients: Lidocaine Comparative Study
Prospective, randomized double-blinded study to investigate hemodynamic changes in valvular cardiac patients during dental treatment with the use of a local anesthesia containing epinephrine.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Loco Regional Anesthesia for Dental Treatment in Cardiac Patients: Comparative Study Between Plain Lidocaine 2% and Lidocaine 2% With Epinephrine 1:100.000|
- arrhythmias [ Time Frame: during procedure ] [ Designated as safety issue: Yes ]
- Arterial pressure [ Time Frame: during procedure ] [ Designated as safety issue: Yes ]
- anxiety [ Time Frame: during and imediately after procedure ] [ Designated as safety issue: Yes ]
|Study Start Date:||January 2003|
|Study Completion Date:||July 2005|
Patients who receive local anesthesia with 2% lidocaine without epinephrine
Patients who receive local anesthesia with 2% lidocaine with 1:100.000 epinephrine
Patients with valvular disease constitute a group in which local anesthesia must be effective to avoid higher release of endogenous catecholamines that could trigger hemodynamic. The study was conducted in the Dental Department of the Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (Brazil). Patients were allocated into two groups through an aleatory numbered table: PL (plain 2% lidocaine, n= 31) and LE (2% lidocaine with 1:100.000 epinephrine, n= 28). The anesthetic amount was registered. DIXTAL monitor (São Paulo- Brazil) captured blood pressure, heart rate, oxygenation and electrocardiogram records.
|Hospital das Clínicas da FMUSP|
|Sao Paulo, Brazil, 05430 010|
|Principal Investigator:||Joaquim E Vieira, MD, PhD||University of Sao Paulo Medical School - FMUSP|