Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy
The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.
Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy Using Multidetector Computed Tomography Scan and Color Doppler Imaging.|
- screening indexes for dysthyroid optic neuropathy [ Time Frame: indexes above 60% of orbital apex crowding were high suspected for DON ] [ Designated as safety issue: No ]
|Study Start Date:||July 2005|
|Study Completion Date:||November 2013|
|Primary Completion Date:||November 2013 (Final data collection date for primary outcome measure)|
1Patients with Graves´orbitophathy.
Patients with Graves´orbitophathy.
2 Patients with detected DON
Patients with Graves´orbitophaty and detected dysthyroid optic neuropathy (DON)
Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging:
Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).
Please refer to this study by its ClinicalTrials.gov identifier: NCT00665795
|General Hospital - University of Sao Paulo - School of Medicine|
|São Paulo, Brazil, 05409 000|
|Study Chair:||Mario L Monteiro, MD, PhD||University of Sao Paulo - School of Medicine|