Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy
The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.
Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy Using Multidetector Computed Tomography Scan and Color Doppler Imaging.|
- screening indexes for dysthyroid optic neuropathy [ Time Frame: indexes above 60% of orbital apex crowding were high suspected for DON ] [ Designated as safety issue: No ]
|Study Start Date:||July 2005|
|Study Completion Date:||November 2013|
|Primary Completion Date:||November 2013 (Final data collection date for primary outcome measure)|
1Patients with Graves´orbitophathy.
Patients with Graves´orbitophathy.
2 Patients with detected DON
Patients with Graves´orbitophaty and detected dysthyroid optic neuropathy (DON)
Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging:
Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).
|General Hospital - University of Sao Paulo - School of Medicine|
|São Paulo, Brazil, 05409 000|
|Study Chair:||Mario L Monteiro, MD, PhD||University of Sao Paulo - School of Medicine|