Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
Pleural effusion is a common complication of cardiac surgery. The aim of this study was to determine the prevalence, characteristics and determinants of clinically significant pleural effusions, defined as those requiring therapeutic pleural drainage.
| Condition |
|---|
|
Pleural Effusion Coronary Artery Bypass |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Retrospective |
| Official Title: | Pleural Effusions Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features. |
- Pleural effusion requiring therapeutic drainage [ Time Frame: within the first 12 months after surgery ] [ Designated as safety issue: No ]
| Enrollment: | 2892 |
| Study Start Date: | January 2004 |
| Study Completion Date: | October 2006 |
| Primary Completion Date: | December 2005 (Final data collection date for primary outcome measure) |
This was a retrospective cohort study of prevalence and characteristics of patients who had a pleural effusion after coronary artery bypass graft, valve replacement or both procedures.
Information was collected on all consecutive patients who underwent CABG surgery and/or valve replacement between January 1, 2004 and December 31, 2005. Demographic information, anthropometric parameters, cardiac and renal function assessments, and comorbid conditions were retrieved from medical files. We also collected data on the type of procedure, whether it was elective or urgent, the number and origin of the grafts, the duration of surgery and of cardiopulmonary bypass and the postoperative complications, including pleural effusions. Clinical presentation and evolution of the effusions as well as pleural fluid characteristics were also studied.
Patients were considered to have a clinically significant pleural effusion when they met at least one of the following criteria: need for thoracentesis, a pleural drainage tube or a hospital readmission due to a pleural effusion that occurred within one year of surgery.
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Patients undergoing coronary artery bypass grafting surgery, heart valve replacement surgery or both procedures.
Inclusion Criteria:
- Coronary artery bypass grafting (CABG)
- Valve replacement
- Combined CABG and valve replacement
- between January 1st, 2004 and December 31st, 2005
Exclusion Criteria:
- Previous CABG
- Pulmonary and/or aortic artery surgery
- Heart or lung transplant
- Pleural effusion present at the time of surgery
Contacts and Locations| Canada, Quebec | |
| Unité de Recherche en Pneumologie, Hôpital Laval | |
| Québec, Quebec, Canada, G1V4G5 | |
| Principal Investigator: | Louis-Philippe Boulet, MD, FRCP(C) | Unité de Recherche en Pneumologie, Hôpital Laval |
More Information
No publications provided by Laval University
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | Louis-Philippe Boulet, Respirologist, Unité de Recherche en Pneumologie, Hôpital Laval |
| ClinicalTrials.gov Identifier: | NCT00665015 History of Changes |
| Other Study ID Numbers: | PEFCS-summer 07 |
| Study First Received: | April 21, 2008 |
| Last Updated: | April 21, 2008 |
| Health Authority: | Canada: Canadian Institutes of Health Research |
Keywords provided by Laval University:
|
pleural effusion coronary artery bypass heart valve replacement |
Additional relevant MeSH terms:
|
Pleural Effusion Pleural Diseases Respiratory Tract Diseases |
ClinicalTrials.gov processed this record on May 16, 2013