Reduction of Abdominal Obesity and Insulin Resistance in Women

This study has been completed.

First Received: April 21, 2008 Last Updated: April 22, 2008 History of Changes

Sponsors and Collaborators:	Queen's University Canadian Institutes of Health Research (CIHR)
Information provided by:	Queen's University
ClinicalTrials.gov Identifier:	NCT00664495

Purpose

The purpose of the study was to assess the effects of equivalent diet- or exercise-induced weight loss and related insulin resistance in abdominally obese women.

Condition	Intervention
Obesity	Behavioral: Diet Weight Loss Behavioral: Exercise Weight Loss Behavioral: Exercise Without Weight Loss

Study Type:	Interventional
Study Design:	Treatment, Randomized, Parallel Assignment
Official Title:	Reduction of Abdominal Obesity and Insulin Resistance in Women

Resource links provided by NLM:

MedlinePlus related topics: Diets Exercise and Physical Fitness Obesity Weight Control

Drug Information available for: Insulin

U.S. FDA Resources

Further study details as provided by Queen's University:

Primary Outcome Measures:

Abdominal Obesity [ Time Frame: 4 months ] [ Designated as safety issue: No ]
Insulin Resistance [ Time Frame: 4 Months ] [ Designated as safety issue: No ]

Study Start Date:	April 1999
Study Completion Date:	December 2003
Primary Completion Date:	December 2003 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
C: No Intervention Control
DWL: Active Comparator Diet Weight Loss	Behavioral: Diet Weight Loss
EWL: Active Comparator Exercise Weight Loss	Behavioral: Exercise Weight Loss
EWS: Active Comparator Exercise Without Weight Loss	Behavioral: Exercise Without Weight Loss

Eligibility

Ages Eligible for Study:	20 Years to 50 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Premenopausal women

Exclusion Criteria:

Smokers and diabetics

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00664495

Locations

Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6

Sponsors and Collaborators

Queen's University

Canadian Institutes of Health Research (CIHR)

Investigators

Principal Investigator:

Robert Ross, PhD

Queen's University

More Information

Publications:

Ross R, Janssen I, Dawson J, Kungl AM, Kuk JL, Wong SL, Nguyen-Duy TB, Lee S, Kilpatrick K, Hudson R. Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial. Obes Res. 2004 May;12(5):789-98.

Responsible Party:	( Queen's University )
Study ID Numbers:	Ross 1999
Study First Received:	April 21, 2008
Last Updated:	April 22, 2008
ClinicalTrials.gov Identifier:	NCT00664495 History of Changes
Health Authority:	Canada: Canadian Institutes of Health Research

Keywords provided by Queen's University:

Obesity, exercise, diet, insulin resistance

Study placed in the following topic categories:

Body Weight
Signs and Symptoms
Hyperinsulinism
Obesity
Metabolic Diseases
Nutrition Disorders

Overweight
Overnutrition
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Disorder
Insulin

Additional relevant MeSH terms:

Body Weight
Signs and Symptoms
Hyperinsulinism
Obesity
Metabolic Diseases

Nutrition Disorders
Overweight
Overnutrition
Insulin Resistance
Glucose Metabolism Disorders

ClinicalTrials.gov processed this record on July 06, 2009