Text Size

Functional Tests in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

This study has been completed.
Sponsor:
Collaborator:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Information provided by (Responsible Party):
Bruna Varanda Pessoa, Universidade Federal de Sao Carlos
ClinicalTrials.gov Identifier:
NCT00660738
First received: April 10, 2008
Last updated: January 22, 2012
Last verified: January 2012
History of Changes
  Purpose

Objectives: to evaluate and compare the responses to the various functional tests, and the concordance between the six-minute walk test in hallway (6MWT) and the of oval track (6MWToT), of treadmill (6MWTT), and of treadmill with inclination (6MWTTI), the six-minute step test (6MST) and the sit-to-stand test (STST), in patients with Chronic Obstructive Pulmonary Disease (COPD), and to correlate the responses with functional state and quality of life. Methods: Ten patients with COPD (71±8years, FEV1<80%predicted) were assessed using the functional tests. A dyspnea was assessed using the London Chest Activity of Daily Living and the Medical Research Council scales; and the quality of life was assessed using the St George's Respiratory Questionnaire (SGRQ).


Condition
Chronic Obstructive Pulmonary Disease

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: Comparison of Different Functional Tests and Relation With Functional State and Quality of Life in Individuals With Chronic Obstructive Pulmonary Disease (COPD)

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Universidade Federal de Sao Carlos:

Enrollment: 11
Study Start Date: January 2007
Study Completion Date: February 2008
Primary Completion Date: February 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
01
Patients with clinical and spirometric diagnosis of COPD, with FEV1<80%

Detailed Description:

Results: In the interests analysis, there was lower walking distance in the 6MWTT and 6MWTTI was observed, to compare in the 6MWT and 6MWToT; the ΔSp,O2 (delta of arterial oxygen saturation measured by pulse oximeter) in the 6MWTTI was significantly greater that in the 6MWT, but not between to change in dyspnea and fatigue/pain in the lower-limbs between rest and exercise of peak (Δ). Concordance and correlation was observed between the lower Sp,O2 of the 6MWT with the 6MWToT, 6MWTT, 6MWTTI, 6MST and STST. Strong correlations was observed between the performances on the 6MST and 6MWT, 6MWToT and 6MWTT; and between the physical activity domain of the SGRQ with the performances in the 6MWT, 6MWToT, 6MWTT,6MST and STST. Conclusion: The functional tests produced similar subjective responses; however, the 6MWTTI caused greater desaturation that 6MWT. The concordance between the 6MWT and the tests performed, suggests acceptable use of any these tests in the physiotherapeutic clinical routine of the individuals COPD. The tests in performed, except the 6MWTTI, shown to be indicators of the quality of life (physical activity domain).

  Eligibility

Ages Eligible for Study:   55 Years to 81 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

chronic obstructive pulmonary disease.

Criteria

Inclusion Criteria:

  • Tiffeneau index<70% e 30%<FEV1<80% predict;
  • no presenting exacerbation during the study period;
  • clinical stability for the four weeks preceding the study outset;
  • no-smokers or ex-smokers.

Exclusion Criteria:

  • being incapable of understanding the scales and questionary;
  • being unable to perform the tests.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00660738

Locations
Brazil
Special Unit of Respiratory Physiotherapy of Federal University of Sao Carlos (UFSCar)
São Carlos, São Paulo, Brazil, 676
Sponsors and Collaborators
Universidade Federal de Sao Carlos
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Investigators
Principal Investigator: Bruna Varanda Pessoa, Master, Physiotherapist Universidade Federal de Sao Carlos
  More Information

Publications:

Responsible Party: Bruna Varanda Pessoa, Master Degree, Universidade Federal de Sao Carlos
ClinicalTrials.gov Identifier: NCT00660738     History of Changes
Other Study ID Numbers: 074/2007
Study First Received: April 10, 2008
Last Updated: January 22, 2012
Health Authority: Brazil: National Committee of Ethics in Research

Keywords provided by Universidade Federal de Sao Carlos:
chronic obstructive pulmonary disease
walking
exercise test
 quality of life
dyspnea
desaturation

Additional relevant MeSH terms:
Lung Diseases
Respiration Disorders
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Respiratory Tract Diseases

ClinicalTrials.gov processed this record on May 23, 2013