Retrospective Postoperative ARDS Study at Vanderbilt University

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Christopher Hughes, Vanderbilt University
ClinicalTrials.gov Identifier:
NCT00656071
First received: April 4, 2008
Last updated: September 5, 2012
Last verified: September 2012
  Purpose

By examining the intraoperative anesthetic characteristics of patients who developed ARDS postoperatively, we hope to identify variables which have a positive or negative association on the development of ARDS.


Condition
ARDS

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Intraoperative Anesthetic Characteristics and the Development of ARDS

Resource links provided by NLM:


Further study details as provided by Vanderbilt University:

Primary Outcome Measures:
  • ARDS [ Time Frame: data pulled from 10/2000 - 08/2007 ] [ Designated as safety issue: Yes ]

Enrollment: 89
Study Start Date: October 2007
Study Completion Date: August 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Control -- postoperative mechanical ventilation patients without ARDS
2
Cases -- postoperative mechanical ventilation patients with ARDS

Detailed Description:

Acute respiratory distress syndrome (ARDS) is a pulmonary disease process that affects post-surgical patients in the intensive care unit and leads to significant patient morbidity and mortality and hospital cost. Extensive research has been conducted in the diagnosis and treatment of ARDS. To date, however, very little research examining the effect of the operative course on the development of ARDS has been reported. By examining the intraoperative anesthetic characteristics of patients who developed ARDS postoperatively, we hope to identify variables which have a positive or negative association on the development of ARDS. Once identified, the variables can be confirmed by future studies and encourage change in clinical care to decrease the occurrence of ARDS in surgical patients.

  Eligibility

Ages Eligible for Study:   11 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

The surgical and post-op patients at VUMC. The collection dates will be from October 1, 2001 until August 31, 2007.

Criteria

Inclusion Criteria:

  • ARDS
  • post-surgical
  • ventilator

Exclusion Criteria:

  • rib fracture
  • pneumonia
  • sepsis
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00656071

Locations
United States, Tennessee
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37212
Sponsors and Collaborators
Vanderbilt University
Investigators
Principal Investigator: Christopher G Hughes, M.D. Vanderbilt University
  More Information

Additional Information:
No publications provided

Responsible Party: Christopher Hughes, Assistant Professor, Vanderbilt University
ClinicalTrials.gov Identifier: NCT00656071     History of Changes
Other Study ID Numbers: CHughes-PGY2
Study First Received: April 4, 2008
Last Updated: September 5, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by Vanderbilt University:
ARDS
Acute respiratory distress syndrome
Adult respiratory distress syndrome
respiratory distress

Additional relevant MeSH terms:
Respiratory Distress Syndrome, Adult
Lung Diseases
Respiratory Tract Diseases
Respiration Disorders

ClinicalTrials.gov processed this record on April 15, 2014